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1 - 20 of 159

Communication-centered Parent-mediated treatment for Autism Spectrum Disorder in South Asia (COMPASS).

DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY

MRC JGHT 7 Full 2017 award - Communicationcentered Parentmediated treatment for Autism Spectrum Disorder in South Asia (COMPASS).

Programme Id GB-GOV-13-OODA-MRC-7USD4VA-HGRZRK2-8QNRQ8W
Start date 2018-4-1
Status Implementation
Total budget £624,454.64

A Novel High Intensity Short Interval Dance Intervention for Non Communicable Disease(NCD) Prevention in Asian Indian Adolescent Girls-THANDAV

DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY

MRC JGHT award to develop a novel intensity short Interval Dance Intervention for Non Communicable Disease(NCD) Prevention in Asian Indian Adolescent Girls-THANDAV

Programme Id GB-GOV-13-OODA-MRC-7USD4VA-FHEY8RA-FDE4WRM
Start date 2022-6-1
Status Implementation
Total budget £37,038.51

Fluconazole plus flucytosine vs fluconazole alone for cryptococcal antigen-positive patients identified through screening: A randomised trial

DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY

MRC Joint Global Health Trial to determine Fluconazole plus flucytosine vs fluconazole alone for cryptococcal antigen-positive patients identified through screening: A randomised trial. The trial aims to compare the efficacy of an oral combination of fluconazole plus flucytosine with fluconazole alone (the current recommended treatment) in reducing all-cause mortality in advanced HIV patients in Tanzania and South Africa.

Programme Id GB-GOV-13-OODA-MRC-7USD4VA-HVWVGAD-XEA8M65
Start date 2021-4-1
Status Implementation
Total budget £1,128,680.84

An International Collaboration to Implement and Evaluate at Scale the Active Prevention and Treatment of Maternal Sepsis (APT-Sepsis Programme)

DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY

MRC Joint Global health Trial to carefully answer the question if the Active Prevention Treatment sepsis programme reduces mothers dying or having the most severe infections will involve a clinical trial. This will be done in Malawi and Uganda.

Programme Id GB-GOV-13-OODA-MRC-7USD4VA-HVWVGAD-QLELZ62
Start date 2021-2-1
Status Implementation
Total budget £796,271.24

Complex intervention to optimise adolescent BMI pre-conception to address the double burden of malnutrition: A RCT in rural and urban South Africa

DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY

MRC Joint Global Health Trial on how to best to intervene working with community health workers to improve the nutritional status of adolescent girls in South Africa

Programme Id GB-GOV-13-OODA-MRC-7USD4VA-HVWVGAD-RQFPRJF
Start date 2021-1-1
Status Implementation
Total budget £703,773.10

Two decades of expansion of primary health care in Latin America: a multi-country evaluation and forecasting study for health-related SDGs

DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY

MRC HSRI award to systematically address all these issues for a comprehensive evaluation of the effectiveness of PHC on the broadest possible range of morbidity and mortality outcomes in Brazil, Colombia, Ecuador and Mexico (BCEM).

Programme Id GB-GOV-13-OODA-MRC-VP6RWB3-QL4LKYW-69X9GTF
Start date 2020-1-1
Status Implementation
Total budget £92,691.29

Learning health systems: fostering participatory learning and action to equip rural health workers as change agents for maternal and newborn care.

DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY

MRC JHSRI l aim is to understand if and how a participatory learning and action (PLA) intervention can improve organisational learning culture amongst rural health workers (HWs) and experiences of person-centred maternal and newborn health (MNH) care amongst women in rural South Africa.

Programme Id GB-GOV-13-OODA-MRC-VP6RWB3-6WYSZDS-SNARALB
Start date 2022-7-1
Status Implementation
Total budget £406,323.92

Regulating e-pharmacy: challenges and opportunities for access and quality of care in LMIC health systems

DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY

MRC JHSRI to assess the performance of e-pharmacies in India and Kenya, analyse the systems that regulate them, and identify opportunities for improving medicine quality, safety and accessibility.

Programme Id GB-GOV-13-OODA-MRC-VP6RWB3-6WYSZDS-35HQKLM
Start date 2022-6-1
Status Implementation
Total budget £442,340.31

GMP manufacture and Phase I clinical trial of a thermostable single-dose rabies vaccine for pre-exposure prophylaxis for children in endemic areas

DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY

MRC BMC: DPFS Full July 2016 award - GMP manufacture and Phase I clinical trial of a thermostable singledose rabies vaccine for preexposure prophylaxis for children in endemic areas

Programme Id GB-GOV-13-OODA-MRC-8DYY2YZ-HCRZY4V-CGZX4RT
Start date 2017-4-24
Status Implementation
Total budget £2,162,957.52

Dissecting the role of host receptor context and cytoskeletal disruption in malaria parasite invasion

DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY

MRC IIB award to exploit generation of novel in vitro derived red blood cell phenotypes in order understand and dissect the dynamic remodelling of host RBC membrane and cytoskeletal proteins that occurs during malaria parasite invasion

Programme Id GB-GOV-13-OODA-MRC-8DYY2YZ-8S4RBSP-MS9VCD5
Start date 2021-9-1
Status Implementation
Total budget £585,248.32

Neurobiological pathways from trauma exposure to child mental health outcomes in a high adversity South African Birth Cohort

DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY

MRC NMHB RM 19 Award looking at the neurobiological pathways from trauma exposure to child mental health outcomes in a high adversity South African Birth Cohort

Programme Id GB-GOV-13-OODA-MRC-8DYY2YZ-4EBFXZL-8XVYM5T
Start date 2019-11-1
Status Implementation
Total budget £663,107.15

Can malaria transmission be prevented through catastrophic failure of gametocyte quiescence?

DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY

MRC Career development fellowship to study the unusual and poorly understood state of quiescence in mature infectious male and female Plasmodium gametocytes that are directly responsible for the transmission of the parasite from humans to mosquitoes.

Programme Id GB-GOV-13-OODA-MRC-VKG6L2G-5NW3M9N-HR3USSR
Start date 2021-2-1
Status Implementation
Total budget £1,146,248.28

A combination efficacy study in Africa of two DNA-MVA- or DNA- Env protein HIV-1 vaccine regimens with pre-exposure prophylaxis (PrEP)

DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY

MRC supplementary funding to support the extension of a European & Developing Countries Clinical Trial Partnership funded HIV efficacy vaccine trial

Programme Id GB-GOV-13-OODA-MRC-MK6NR8M-EPCELQG-BTZDKEX
Start date 2023-4-1
Status Implementation
Total budget £978,387.08

ODA Programmes within MRC Clinical Trials Unit

DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY

Clinical Trials Unit Southampton - International reputation for making important scientific discoveries in the lab and translating them into successful clinical treatments. Through links across the University, the NHS and industry able to push the boundaries of medical research and address key healthcare issues. There are a number of programmes under the CT unit: 1) The Blood borne viruses programme is currently focussed on two blood borne viruses with enormous global burden, and long term health and economic impact. DAC countries currently supported are Kenya, Uganda, South Africa, Zimbabwe, Vietnam, Thailand, Morocco, Mozambique, Egypt and Ukraine. The outcomes of these trials and studies will promote economic development and welfare by reducing the burden placed on these countries by these blood borne viruses 2) Respiratory infection: The DAC countries supported from the COVID-19 and TB trials being conducted in the respiratory programme are: Zimbabwe, Uganda, Mozambique, Ethiopia, South Africa, Zambia, India and Vietnam 3) The Syndromics programme has two sub-themes, the “acutely sick child in Africa” and “serious bacterial infections and antimicrobial resistance”, both of which are addressing development challenges by developing and testing interventions to reduce mortality and morbidity in children and adults in LMIC through programmes of randomised controlled trials, and associated epidemiological studies addressing questions around management and treatment. DAC countries currently supported are Kenya, Uganda, Mozambique, Ghana, Malawi, South Africa, Zambia, Bangladesh, Vietnam, Thailand, India, Brazil, China. The outcomes of these trials and studies will promote economic development and welfare by reducing the burden placed on these countries by acute and infectious diseases, particularly loss of economic output in adult carers due to illness in their children

Programme Id GB-GOV-13-OODA-MRC-Q8TS83Q-E8PRU76-47RVW2C
Start date 2013-8-1
Status Implementation
Total budget £18,050,470

ODA Programmes within MRC Centre for Virus Research

DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY

The MRC-University of Glasgow Centre for Virus Research (CVR) is home to an internationally leading critical mass of virologists, entirely focused on the study of human viral diseases and viruses at the human-animal interface. Established in 2010 as a partnership between the University and the Medical Research Council (MRC), the CVR contributes to national virology capability and supports the global response to viruses and the diseases they cause.

Programme Id GB-GOV-13-OODA-MRC-Q8TS83Q-G7VJA9E-5L7Y3LW
Start date 2013-4-1
Status Implementation
Total budget £8,967,470.94

ODA Programmes within Francis Crick Institute

DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY

ODA Programmes within Francis Crick Institute - The Francis Crick Institute is a biomedical research institute working with organisations across academia, medicine and industry to make discoveries about how life works.

Programme Id GB-GOV-13-OODA-MRC-Q8TS83Q-7G5GQF9-QC27PG6
Start date 2017-4-1
Status Implementation
Total budget £68,620,606.56

MRC funding for Programmes and Awards at MRC Uganda Unit

DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY

MRC funding for Programmes and Awards at MRC Uganda Unit - Science is delivered through six programmes feeding into each theme, including HIV Epidemiology and Intervention, Cancer Epidemiology, Social Aspects of Health Across the Life-Course, Pathogen Genomics Phenotype and Immunity, Immunomodulation and Vaccines, and NCD Phenotyping.

Programme Id GB-GOV-13-OODA-MRC-Q8TS83Q-YJNMS5D-S47HE2Q
Start date 2006-4-1
Status Implementation
Total budget £58,902,303.20

MRC funding for Programmes and Awards at MRC Gambia Unit

DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY

The MRC Unit The Gambia (MRCG) is the MRC’s single largest investment in medical research in a low and middle income country. Research including viral disease, maternal and neonatal health, early child development and Nutrition including the evaluation of interventions for the control of diseases of public health importance within The Gambia

Programme Id GB-GOV-13-OODA-MRC-Q8TS83Q-EWL7E7G-6QF235V
Start date 2006-4-1
Status Implementation
Total budget £132,867,248.33

Phase III, Multicentre, Randomized, Double-blind, Placebo-controlled Study to Evaluate Efficacy of Probiotic Supplementation for Prevention of Neona

DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY

MRC Joint Global Health Trial in India, The current trial aims to find out if feeding probiotics daily for 30 days during the first month of life would prevent these infections. Remaining healthy in the first month is important as it allows the newborns t

Programme Id GB-GOV-13-OODA-MRC-7USD4VA-K8E2MJ9-S88N6UQ
Start date 2019-9-1
Status Implementation
Total budget £319,024.63

Nutrition and the epigenome: early environmental factors influencing human developmental programming

DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY

iMRC PSMB award seeking to better understand HOW diet affects the laying down of these methylation marks, WHICH areas of the methylome are especially sensitive to such influences, HOW they influence the development of the placenta and fetus, and ultimately WHAT effects these changes have on the baby's development and life-long health. This activity benefits Malawi;Uganda.

Programme Id GB-GOV-13-OODA-MRC-8DYY2YZ-2L96RXD-62FQAER
Start date 2020-10-1
Status Implementation
Total budget £1,901,032.76

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