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Establishing and enhancing veterinary surveillance of antimicrobial resistance (AMR) and use in low- and middle-income countries (LMICs)
Department for Environment, Food, and Rural Affairs
This project aims to help establish effective surveillance for longer term capacity building for AMR in the terrestrial and aquatic veterinary sectors in selected LMICs, and to enhance veterinary medicines regulatory training.
Project identifier:
GB-GOV-7-VMD-AMR001
Start Date:
2019-09-16
Activity Status:
Implementation
Total Budget:
£400,000
Land Degradation Neutrality Fund
Department for Environment, Food, and Rural Affairs
The LDN Fund invests in projects which reduce or reverse land degradation and thereby contribute to ‘Land Degradation Neutrality’. The LDN Fund is co-promoted by the Global Mechanism of the United Nations Convention to Combat Desertification (UNCCD) and Mirova. It is a public-private partnership using public money to increase private sector investment in sustainable development. The fund invests in sustainable agriculture, forestry and other land uses globally. The Fund was launched at the UNCCD’s COP 13 in China in 2017.
Project identifier:
GB-GOV-7-PO009-LDN
Start Date:
2019-12-12
Activity Status:
Implementation
Total Budget:
£10,000,000
Fleming Fund – Country and Regional Grants and Fellowships Programme
UK - Department of Health (DH)
The Fleming Fund helps low- and middle-income countries to fight antimicrobial resistance. A management agent has been appointed to deliver: country grants 24 low- and middle-income countries, regional grants in West Africa, East and Southern Africa, South Asia and South East Asia, and a global fellowships programme. These initiatives aim to improve laboratory capacity and diagnosis as well as data and surveillance of antimicrobial resistance (AMR).
Project identifier:
GB-GOV-10-FF_MA
Start Date:
2016-10-10
Activity Status:
Implementation
Total Budget:
£258,497,532.75
Strengthening private-sector medicine systems to tackle the persistence of poor-quality medicines in Africa: a proof-of-concept study
UK - Department for Business, Energy and Industrial Strategy (BEIS)
Poor-quality medicines, containing little or no active ingredient - whether through deliberate fraud, poor manufacturing practice or post-manufacture deterioration - represent a major public health threat in low/middle-income countries (LMICs): responsible for more than 200,000 under-5 deaths each year in Africa and contributing to antimicrobial drug resistance. Efforts by governments and international agencies to curb the problem through improving detection rates, tightening regulation and public education have been hampered by the economic realities of medicine supply in resource-poor, high-need contexts, but also - we suggest - by a failure to apprehend fully the complex workings of medicine supply systems, particularly beyond the public sector. Private-sector medicine systems can be characterised as 'complex systems' involving multiple dispersed actors with no central organising authority. Recent developments in the study of complex systems have revealed how the actions of individuals can combine to have non-intuitive effects on the system as whole. This has significant implications for well-intentioned policy interventions based on 'common sense' intuition, which may have unwelcome unanticipated consequences. Our ultimate goal is to understand - and predict - the workings of complex medicine systems in order to inform effective interventions to minimise the penetration of poor-quality products in LMICs. This will require: mapping complete medicine supply chains; understanding the motivations/behaviours of buyers, sellers and regulators; developing sophisticated computational models to simulate the system; and engaging stake-holders to co-design evidence-based interventions. This is an ambitious project which needs careful groundwork through a proof-of-concept study with the following objectives and activities: (1) To assess fieldwork feasibility in these contexts and validate research instruments: Very few people have attempted to trace a full medicine supply chain in an under-regulated context. In order to assess feasibility, safety and ethical issues, we will map a limited number of medicine supply chains starting at retail outlets across Ghana and Tanzania and moving upwards to point of manufacture, obtaining as much relevant information as possible at each stage. Research instruments will be validated in each local context, and re-validated across contexts to ensure consistency. (2) To develop our understandings of the structure and operation of private-sector medicine systems: Geographically weighted analysis will be employed to describe the structure/organization of supply systems (length, number of transaction points, degree/level of vertical 'collapse', etc.) and investigate spatial dependencies in the data. Thematic analysis of ethnographic data and secondary sources will be used to understand actors' decision-making and behaviour at each point. (3) To build Agent-Based Models (ABMs) simulating medicine systems, based on empirical data: We will build a sequence of ABMs simulating medicine supply systems in Ghana and Tanzania as 'complex systems'. These models will allow us to understand, and ultimately predict, how individual behaviours might affect the system as a whole. We will develop 'user-friendly' models to use with policy-makers, highlighting potential unintended consequences of interventions. (4) To develop and evaluate strategies for engaging relevant actors (market, regulatory, political) in the research and intervention design: In each country, we will convene National Stake-holder Groups (NSGs), with policy, regulatory and high-level market actors and Project Working Groups (PWGs), comprising 'on-the-ground' supply-chain actors (buyers, sellers and regulators). Through a series of collaborative workshops, we will work with 'user-friendly' models to identify potential 'bottlenecks' or problematic behavioural logics that might underpin interventions.
Project identifier:
GB-GOV-13-FUND--GCRF-MR_T022132_1
Start Date:
2020-03-01
Activity Status:
Implementation
Total Budget:
£0
Adapting the health system in Ghana to reach the urban poor
UK - Department for Business, Energy and Industrial Strategy (BEIS)
In rural areas, Ghana has a well-established programme of community-based nurses, community health officers and volunteers working with rural communities to improve maternal and child health. The approach is called Community Health Planning and Services (CHPS) and evaluations in rural areas have shown that the approach has halved all maternal deaths and with increased access to family planning, reducing by one the number of children a woman gives birth to. While successful in rural areas, the approach has not yet been extended to urban areas. Ghana is urbanising rapidly and inequalities between the rich and poor are unacceptably high, with children under the age of 14 in poor urban communities five times more likely to die than the general urban population. Extending CHPS to poor urban communities is now a top government priority. This proposal has been put together by health systems researchers and policy makers embedded within Ghana's health services (GHS) and the national CHPS programme. Our aim is to conduct the foundation work needed to scale-up CHPS so that the poorest, marginalised urban residents can benefit from the approach. We will engage closely with three urban communities, each with different variations of urban poverty, for example informal settlements or more mixed, well-established neighbourhoods. Our team includes senior GHS staff, including the head of CHPS, head of nursing research and a strong team of health systems researchers. Ghanaian public health registrars who have worked throughout GHS, with expertise in research methods, will work alongside UK public health registrars (at no salary cost to the project). They will conduct two focus groups in each of the 3 areas. Participants will include women with children facing a variety of challenges to accessing health care. We will conduct approx. 24 interviews with marginalised groups and also community leaders. The registrars will conduct a desk review of urban community health initiatives. We will collect details of current services provided in the 3 areas and their costs. Key decision makers from within the CHPS programme and GHS will come together for a workshop to design a prototype urban CHPS model and identify all materials, guidelines and training that need to be developed. Our team will develop the practical tools and revise them based on learning throughout the project. CHPS staff and volunteers will be trained to deliver the new model and will begin implementation in the three areas. Our team will facilitate participatory action research groups with the CHPS staff, community members in each of the areas. The groups will identify issues, agree on and implement solutions and then observe the results. This will lead to a continual cycle of learning and development. The registrars will document this process, collect cost and service data to estimate cost and increase in utilisation and qualitative data with marginalised groups to inform improvement. This will provide valuable new knowledge on how to engage communities and develop an urban health system to reach the most vulnerable. We will draw on a theoretical framework that spells out different components to consider in community engagement. This will ensure that the model we develop considers all aspects of creating a successful and sustainable community engagement model. Our findings will also allow us to propose modifications to the framework which is currently based on evidence from high income countries. A final workshop with CHPS and CHS decision makers will enable the detailed development of a plan to scale-up the model across urban Ghana. It will also enable us to plan for future large scale evaluation. By the end of the project, a full suite of policy and practice documents will be available to enable scale-up across urban areas. We will establish a centre of excellence for Urban CHPS to maintain the culture of research to continually evaluate and improve urban CHPS as it is scaled up.
Project identifier:
GB-GOV-13-FUND--GCRF-MR_T022787_1
Start Date:
2020-09-01
Activity Status:
Implementation
Total Budget:
£0
GCRF_NF335 COVID19: Greening the Social and Economic Recovery in Ghana and Zambia
UK - Department for Business, Energy and Industrial Strategy (BEIS)
This project will support a clean and resilient recovery from the Covid-19 pandemic in Ghana and Zambia. It will work with research partners, governments and other organisations in those countries to develop strategies that integrate economic recovery and climate change policies. Ghana and Zambia have been chosen because there is an opportunity to build on existing collaborations; there is a clear demand from policy makers for this research; and they have important differences that will enable lessons to be learned in other countries. The project has five main objectives. It will: 1. Understand the drivers, challenges and opportunities for a clean, resilient recovery in Ghana and Zambia 2. Investigate options for a clean, resilient recovery through the co-creation of participatory pathways for future development 3. Quantify the socio-economic, energy and climate implications of a clean, resilient recovery 4. Support government decision-making on recovery, climate action and development planning, including through information-sharing and the adaption of clean, resilient recovery initiatives from other contexts 5. Strengthen capacity, share knowledge and create equitable and enduring partnerships The project will focus in particular on the development and implementation of revised Nationally Determined Contributions (NDCs). Revised NDCs need to be submitted to the UN Framework Convention on Climate Change before COP26, which will be held in Glasgow in late 2021. This integration is critical not only for social and economic recovery in the short-term, but also for avoiding lock-in to carbon intensive development pathways that could undermine long-term resilience.
Project identifier:
GB-GOV-13-FUND--GCRF-EP_V043064_1
Start Date:
2020-10-27
Activity Status:
Implementation
Total Budget:
£518,220.26
British Academy Coherence & Impact - Challenge-led grants: Early Childhood Education
UK - Department for Business, Energy and Industrial Strategy (BEIS)
The projects funded under this programme aim to provide critical knowledge to inform policy-making in the education and broader learning domain, while recognising the necessary interplay of education with health, nutrition, gender equality and other disciplines and sectors.
Project identifier:
GB-GOV-13-GCRF-CImChlGECE
Start Date:
2019-10-01
Activity Status:
Implementation
Total Budget:
£4,321,513
Royal Academy of Engineering Core - Engineering a Better World
UK - Department for Business, Energy and Industrial Strategy (BEIS)
Engineering a Better World is a unique programme focused on achieving sustainable development, through innovative, collaborative, challenge-led engineering. COVID-19
Project identifier:
GB-GOV-13-RAENG-GCRF-04
Start Date:
2019-09-16
Activity Status:
Implementation
Total Budget:
£1,338,436
Royal Academy of Engineering Core - Frontiers of Engineering for Development
UK - Department for Business, Energy and Industrial Strategy (BEIS)
Frontiers of Engineering for Development is a series of interdisciplinary symposia that facilitates national and international collaboration to tackle global development challenges. The event brings together a select group of around 60 emerging UK and global engineering and international development leaders from industry and academia to discuss pioneering technical work and cutting-edge research for international development from a diversity of engineering fields. Seed funding is available to progress some of the best ideas coming out of the event. COVID-19
Project identifier:
GB-GOV-13-RAENG-GCRF-07
Start Date:
2016-12-01
Activity Status:
Implementation
Total Budget:
£2,028,324.76
Royal Academy of Engineering Core - Engineering for Development Research Fellowships
UK - Department for Business, Energy and Industrial Strategy (BEIS)
The Royal Academy of Engineering offers Research Fellowships each year to outstanding early-career researchers to support them to become future research leaders in engineering.
Project identifier:
GB-GOV-13-RAENG-GCRF-06
Start Date:
2016-08-01
Activity Status:
Implementation
Total Budget:
£4,173,814.18
Royal Academy of Engineering Academies Collective Fund: Resilient Futures - Frontiers of Development
UK - Department for Business, Energy and Industrial Strategy (BEIS)
Frontiers of Development is part of the Joint Resilient Futures Initiative which is a collaboration between all four UK Academies under the GCRF. The aim of the JRF initiative is to construct a pipeline in the UK and the developing world for interdisciplinary researchers focused on tackling development challenges in a sustainable manner.
Project identifier:
GB-GOV-13-RAENG-GCRF-08
Start Date:
2017-10-24
Activity Status:
Implementation
Total Budget:
£1,412,850.85
Royal Academy of Engineering Core - Higher Education Partnerships in Sub-Saharan Africa
UK - Department for Business, Energy and Industrial Strategy (BEIS)
The Higher Education Partnerships in sub-Saharan Africa Programme (HEP SSA) – supported by the Anglo American Group Foundation and the UK Government through the Global Challenges Research Fund – was established by the Royal Academy of Engineering in 2016, following the successful pilot scheme, Enriching Engineering Education Programme. COVID-19
Project identifier:
GB-GOV-13-RAENG-GCRF-05
Start Date:
2016-07-01
Activity Status:
Implementation
Total Budget:
£78,852.39
Pest Risk Information Service (PRISE)
UK - Department for Business, Energy and Industrial Strategy (BEIS)
An estimated 40% of the world’s crops are lost to pests (including insects, mites and plant pathogens), impacting on the ability of smallholder farmers to feed their families and also affecting international trade and food supply chains. By alerting them to the potential presence of pests, this project aims to enable farmers to manage outbreaks more effectively using Integrated Pest Management methods. These techniques have many advantages, such as the reduction of the use of inappropriate pesticides that lead to human and environmental benefits as well as reducing spend on unnecessary spraying.
Project identifier:
GB-GOV-13-GCRF-UKSA_NS_UKSA-031
Start Date:
2016-10-01
Activity Status:
Implementation
Total Budget:
£6,390,198.57
Calcium supplementation to prevent pre-eclampsia in Low- and Middle-Income Countries: IPD meta-analysis, network meta-analysis and economic evaluation
UK - Department for Business, Energy and Industrial Strategy (BEIS)
WHAT IS THE PROBLEM? Pre-eclampsia, a condition in pregnancy associated with high blood pressure and protein in the urine, is a major cause of avoidable deaths in mothers and babies, particularly in low and middle-income countries. Calcium supplements in pregnancy could prevent pre-eclampsia and potentially save 21,500 mothers every year from dying in these countries. Although calcium is on the national essential medicines list of these countries, and the World Health Organization (WHO) recommends high-dose calcium (>1.5g/day) to prevent pre-eclampsia, calcium deficiency in pregnancy continues to be a major preventable public health challenge. We can attribute this to the reluctance of mothers to take large, unpalatable high-dose calcium tablets 3-times a day that is often associated with side effects such as vomiting and constipation. Furthermore, large numbers of bulky tablets pose logistical difficulties with transport and storage, limiting their availability in rural areas. The healthcare professionals also have concerns about the large calcium doses affecting the absorption of iron needed to treat anaemia. WHAT NEEDS TO BE DONE? There is an urgent need for us to identify a) the group of women who will benefit the most from calcium supplementation (based on individual characteristics) b) the most effective and acceptable minimal dose of calcium, and c) the best time to start the supplement to prevent pre-eclampsia and complications. Policymakers and healthcare professionals also need information on the barriers to the uptake of calcium and its implementation, and the cost implications of supplementation within limited healthcare resources. WHAT HAS BEEN DONE SO FAR? To-date, despite over 30,000 women participating in numerous studies on calcium supplementation to prevent pre-eclampsia, we were able to answer the above questions due to differences in the characteristics of women, the dosage and timing of calcium in these studies. Our international collaborative network (i-CIP) has established a partnership between researchers from low, middle- and high-income countries who conducted the above studies, WHO guideline developers, and experts on calcium supplementation in pregnancy to answer the gaps in research. WHAT DO WE PLAN TO DO? In this proposal, we plan to combine the data from individuals who participated in studies on calcium supplementation by a technique called 'IPD meta-analysis' to determine if the effects of calcium differed between different groups of women, and if it varied according to the dose and duration of calcium use. We will obtain the views of mothers and healthcare professionals through surveys and interviews on what they consider may hinder the uptake and use of the calcium supplementation strategy that we find to be most effective. We will study the costs of calcium supplementation against the costs saved in low- and middle-income countries by avoiding pre-eclampsia and its complications. This economic model will be provided in a format that can be used by experts in other countries to determine the relevant economic impact. Research capacity strengthening of our partners is the key to the long-term sustainability of the project. WHAT DO WE EXPECT WILL HAPPEN? We expect our findings to lead to an update of the existing WHO guidelines on calcium supplementation in pregnancy, inform policymakers on optimal strategies and costs to promote calcium supplementation, reduce calcium deficiency in pregnant women, and improve outcomes for mother and baby by preventing pre-eclampsia. We planned this proposal in partnership with the patient and public involvement groups so that women are involved in the co-development of the study and dissemination. Our collaboration with WHO (Reproductive health, Nutrition, Human Reproduction Programme HRP Alliance) is key to the development and dissemination of our work through guidelines and existing networks.
Project identifier:
GB-GOV-13-FUND--GCRF-MR_T038861_1
Start Date:
2021-01-01
Activity Status:
Implementation
Total Budget:
£404,049.72
British Academy Coherence & Impact - Challenge-led grants: Urban Infrastructures of Well-being
UK - Department for Business, Energy and Industrial Strategy (BEIS)
This programme supports interdisciplinary research across the social and engineering sciences and the humanities looking to explore how formal and informal infrastructures interact to affect the well-being of people in cities across the Global South.
Project identifier:
GB-GOV-13-GCRF-CImChlGUWB
Start Date:
2019-10-01
Activity Status:
Implementation
Total Budget:
£5,838,971
British Academy Coherence & Impact - Youth Futures
UK - Department for Business, Energy and Industrial Strategy (BEIS)
The projects funded under this programme support research which brings a much-needed youth-led perspective on the UN’s 2030 Sustainable Development Agenda. They involve genuine interdisciplinarity, collaborative work that extends beyond the standard research model, and policy thinking based on close understanding of, and working with, young people at various stages of ‘getting by’.
Project identifier:
GB-GOV-13-GCRF-CImYF
Start Date:
2020-01-01
Activity Status:
Implementation
Total Budget:
£5,760,000
Royal Academy of Engineering Core - Africa Catalyst
UK - Department for Business, Energy and Industrial Strategy (BEIS)
GCRF Africa Catalyst aims to strengthen professional engineering bodies in sub-Saharan Africa so that they can effectively promote the profession, share best practice and increase local engineering capacity, to help drive development. This is supported by high-quality research focusing on expanding the evidence base for the importance of robust engineering institutions and the role they play in delivering sustainable growth, and mapping engineering capacity and diversity in sub-Saharan Africa.
Project identifier:
GB-GOV-13-RAENG-GCRF-01
Start Date:
2016-10-01
Activity Status:
Implementation
Total Budget:
£3,288,252.17
Tackling Serious and Organised Crime in Ghana (SOCG)
UK - Foreign, Commonwealth and Development Office
This programme will seek to reduce the negative impact that SOC has on Ghana’s development, by improving governance and raising awareness, commitment and capacity to address it within government, civil society and business. In doing so, it will address direct threats to the UK, and support wider UK security objectives.
Project identifier:
GB-GOV-1-301282
Start Date:
2021-09-27
Activity Status:
Implementation
Total Budget:
£3,585,000
FCDO Prosperity Fund: Overseas Development Assistance (ODA)
UK - Foreign, Commonwealth and Development Office
FCDO Prosperity Fund: Overseas Development Assistance (ODA)
Project identifier:
GB-GOV-3-PF
Start Date:
2016-04-01
Activity Status:
Implementation
Total Budget:
£37,951,860.87
Ghana Partnerships Beyond Aid Programme
UK - Foreign, Commonwealth and Development Office
To improve governance and accountability in Education, Health and Social Protection sectors and contribute to policy and research.
Project identifier:
GB-1-203640
Start Date:
2020-01-22
Activity Status:
Implementation
Total Budget:
£12,719,552