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Global Antimicrobial Resistance Innovation Fund (GAMRIF) - InnoVet AMR: Innovative Veterinary Solutions for AMR with IDRC

UK - Department of Health and Social Care (DHSC)

InnoVet-AMR is a partnership between DHSC and the International Development Research Centre (IDRC) aimed at reducing the emerging risk that antimicrobial resistance (AMR) in animals poses to global health and food security. InnoVet-AMR will fund research to develop new animal vaccines and other innovations to fight AMR in livestock (swine and poultry) and aquaculture production, particularly in low- and middle-income countries (LMICs). Through InnoVet-AMR, IDRC and DHSC aim to achieve two main objectives: (1) support research that will identify innovative veterinary solutions, including vaccines and alternative solutions, to reduce the use of antimicrobials in livestock and aquaculture operations in LMICs; (2) build effective partnerships to better coordinate discovery, development and sustainable delivery of affordable innovative veterinary solutions to reduce the use of antimicrobials in livestock and aquaculture operations in LMICs. Projects funded through the Global AMR Innovation Fund (GAMRIF) will primarily benefit people in LMICs, where the burden of drug-resistant infection is greater.

Programme Id GB-GOV-10-GAMRIF-WP3-InnoVet-AMR
Start date 2018-6-14
Status Implementation
Total budget £23,471,427

Global Antimicrobial Resistance Innovation Fund (GAMRIF) - UK-Argentina: tools to tackle AMR in the Environment

UK - Department of Health and Social Care (DHSC)

This is a bilateral partnership with Argentina to support research to tackle antimicrobial resistance (AMR) in agriculture and the impact on the environment. Successful projects are a partnership of UK companies and research orgnisations, with Argentinian companies and research organisations. The competition and partnership will be delivered in the UK by the Biotechnology and Biological Sciences Research Council (BBSRC) in partnership with the Natural Environment Research Council (NERC), both part of UK Research and Innovation (UKRI), and delivered and matched-funded, on a resource basis, by the National Scientific and Technical Research Council (CONICET) in Argentina. The aim of this partnership is to generate new knowledge and provide a deeper evidence base that can help to reduce the impact of drivers of AMR in the environment from agricultural sources as they apply to Argentina and low- and middle- income countries (LMICs). This includes research towards the development of theroretical frameworks for surveillance and reporting on AMR and antibiotics, and research towards the development of strategies for manure, slurry and waste management. Projects are also required to produce outputs that translate research into policy, such as policy briefings or best practice position papers for LMICs. Projects funded through the Global AMR Innovation Fund (GAMRIF) will primarily benefit people in LMICs, where the burden of drug-resistant infection is greater.

Programme Id GB-GOV-10-GAMRIF-WP4-UK-Argentina
Start date 2018-4-1
Status Implementation
Total budget £5,100,000

Global Antimicrobial Resistance Innovation Fund (GAMRIF) - Accelerating Antibacterial Innovation with CARB-X

UK - Department of Health and Social Care (DHSC)

Through the Global AMR Innovation Fund (GAMRIF), the UK Department of Health and Social Care (DHSC) has invested £20 million over three years in Boston University’s Combating Antibiotic Resistant Bacteria Accelerator (CARB-X), which is a non-profit, multi-donor international partnership that supports innovative early product research and development focused on the most dangerous drug-resistant bacteria. This contribution will invest in high-value, innovative research to accelerate the development of products to reduce the harm from drug-resistant infections. The aim of this project is to invest in high-value, innovative research to accelerate the development of products up to and including Phase I to reduce the harm to human health, welfare and economic growth from drug-resistant infections. In particular, the programme will focus on prevention (including vaccines) and alternatives to antibiotics for humans as primarily and directly relevant to people in low- and middle-income countries (LMICs). Projects funded through GAMRIF will primarily benefit people in LMICs, where the burden of drug-resistant infection is greater.

Programme Id GB-GOV-10-GAMRIF-WP2-CARB-X
Start date 2018-5-16
Status Implementation
Total budget £69,186,320

Global Antimicrobial Resistance Innovation Fund (GAMRIF)

UK - Department of Health and Social Care (DHSC)

Global Antimicrobial Resistance (AMR) Innovation Fund Programme

Programme Id GB-GOV-10-GAMRIF
Start date 2017-4-1
Status Implementation
Total budget £141,168,888

Global Antimicrobial Resistance Innovation Fund (GAMRIF) - Innovation in AMR Diagnostic Tools with FIND

UK - Department of Health and Social Care (DHSC)

FIND is a global non-profit product development partnership that aims to develop, evaluate and deliver high-quality affordable diagnostic tests for poverty-related diseases. UK Department of Health and Social Care (DHSC) funding through the Global AMR Innovation Fund (GAMRIF) will support FIND’s work to enhance the impact of diagnostic tools for antimicrobial resistance (AMR), to support improved AMR surveillance and antibiotic stewardship. This work has two areas of focus: 1) to develop technological methods to connect data from patient testing and health provider consultations to larger data systems, such as national and international AMR surveillance programmes. This will lead to improved antibiotic use and AMR surveillance through increased access of data; and 2) to develop a new diagnostic technologies for drug-resistant gonorrhea, which will enable improved diagnosis and therefore use of new antibiotics. Projects funded through GAMRIF will primarily benefit people in low- and middle-income countries, where the burden of drug-resistant infection is greater.

Programme Id GB-GOV-10-GAMRIF-WP5-FIND
Start date 2018-5-16
Status Implementation
Total budget £18,616,637

Global Antimicrobial Resistance Innovation Fund (GAMRIF) - Vaccine Innovation with BactiVac

UK - Department of Health and Social Care (DHSC)

Vaccine Innovation with BactiVac is a partnership between the UK government and the Bacterial Vaccinology Network (BactiVac) to support the development of vaccines for AMR in humans and animals. The UK government has invested up to £1 million over one year into BactiVac, which is one of 5 networks that are supported by the Global Challenges Research Fund (GCRF) Networks in Vaccines Research & Development. This is co-funded by the Medical Research Council (MRC) and Biotechnology and Biological Sciences Research Council (BBSRC). The primary aim of this investment is to support new, diverse research projects to gain preliminary data and encourage establishment of new research partnerships, and allow these collaborations to build a track record, which will allow them to attain further funding. It is expected that some of these projects will fail, yet the dissemination of both positive and negative research outcomes is valuable and expected. Funded projects will undertake early stage research and development with catalyst pump-priming funding around the world to help drive the development and uptake of vaccines for antimicrobial resistance (AMR) for the benefit of people in low- and middle-income countries (LMICs). Projects funded through the Global AMR Innovation Fund (GAMRIF) will primarily benefit people in LMICs, where the burden of drug-resistant infection is greater.

Programme Id GB-GOV-10-GAMRIF-BACTIVAC
Start date 2019-2-1
Status Implementation
Total budget £2,799,961

UK Public Health Rapid Support Team - Rapid investigation and response

UK - Department of Health and Social Care (DHSC)

"Created in 2016, the UK-PHRST is the primary arm of Her Majesty’s Government to provide and coordinate the UK’s public health response to outbreaks in LMICs. The UK-PHRST is a unique collaboration between Public Health England and the London School of Hygiene and Tropical Medicine with input from a number of academic partners. The UK-PHRST’s remit covers outbreak response, research, and capacity building, as components of its integrated triple mandate: • Rapidly investigate and respond to disease outbreaks at their source in LMICs eligible for UK Official Development Assistance (ODA), with the aim of stopping a public health threat from becoming a broader health emergency • Conduct research to generate an evidence base for best practice in epidemic preparedness and response • Build capacity for improved and rapid national response to disease outbreaks in LMICs and contribute to supporting implementation of IHR at the request of national governments or international stakeholders such as WHO. The UK-PHRST rapidly deploys a standing team of multidisciplinary public health professionals and researchers as required in countries that are a priority for the UK’s ODA programme. The UK-PHRST full-time Core Deployable Team consists of specialists in epidemiology, laboratory microbiology, infection prevention and control, clinical case management and clinical research, social science, data management and logistical support who are available to deploy within 48 of an approved request. Reservists and Field Epidemiology Training Programme (FETP) Fellows complement this team, providing surge capacity and specialist expertise when needed. The UK-PHRST is financed through UK Official Development Assistance (ODA) funding through the Department of Health and Social Care. The UK-PHRST Director is the accountable person to the UK Government, through PHE, for delivery of the UK-PHRST objectives." "The UK-Public Health Rapid Support Team is a key international partner in epidemic disease response. We partner with low- and-middle income countries to respond to infectious disease outbreaks before they can develop into global health emergencies. We work closely with international organisations, partner country governments and non-governmental organisations to: - Rapidly investigate and respond to disease outbreaks at their source in LMICs eligible for UK Official Development Assistance, with the aim of stopping a public health threat from becoming a broader health emergency - Conduct research to generate an evidence base for best practice in epidemic preparedness and response - Strengthen capacity for improved national response to disease outbreaks in LMICs We are an innovative partnership between the UK Health Security Agency and the London School of Hygiene & Tropical Medicine, funded with UK aid by the UK Department of Health and Social Care." The UK Public Health Rapid Support Team (UK -PHRST) has the following main objectives: 1) Within ODA eligible countries to support the rapid investigation and response to disease outbreaks at source, with the aim of stopping a public health threat becoming a health emergency. 2) Conduct rigorous research to aid epidemic preparedness and response and improve future response. 3) Generate an evidence base for best practice in disease outbreak interventions within ODA eligible countries. 4) Train a cadre of public health reservists for the UK -PHRST who can be rapidly deployed to respond to disease outbreaks. 5) Build capacity in-country for an improved and rapid national response to disease outbreaks and contribute to supporting implementation of the International Health Regulations (IHR).

Programme Id GB-GOV-10-UKPHRST-PHE
Start date 2016-4-1
Status Implementation
Total budget £18,932,451.65

Conflict, Stability and Security Fund (CSSF)

UK - Foreign, Commonwealth and Development Office

Conflict, Stability and Security Fund (CSSF)

Programme Id GB-GOV-3-CSSF
Start date 2017-4-1
Status Implementation
Total budget £1,168,915,063

Umoyo Wathu Health System Strengthening Programme

UK - Foreign, Commonwealth Development Office (FCDO)

To reduce rates and inequalities in maternal, under-5 and new-born deaths; as well as reduce stunting in under-5s, by strengthening the quality and coverage of a package of essential health services through lower level district administration. The programme will increase the provision and uptake of quality, highly cost effective life-saving primary healthcare services provided free at the point of use, and so better protect the most vulnerable against the financial consequences of ill health. By 2028, the programme will contribute to reducing maternal mortality from 439 to 350 per 100,000 births; neonatal mortality from 27 to 22 per 1,000 live births; child mortality from 64 to 48 per 1,000 live births; stunting in children under five years of age reduced from 37% to 31%; and impact of communicable disease outbreaks and epidemics.

Programme Id GB-GOV-1-300150
Start date 2019-11-21
Status Implementation
Total budget £117,115,132

Better Lives for Somali Women and Children

UK - Foreign, Commonwealth Development Office (FCDO)

To achieve UK's manifesto commitment of reducing preventable deaths, the Better Lives for Somali Women and Children will continue to respond to the health and nutrition needs of the Somali people. There will be a continued focus on delivering an essential package of health services. The programme will strengthen the Somali Health Authorities oversight of service provision, which will in turn promote local accountability and allow them increasingly to respond to the needs of their populations. This programme approach aims to support long term sustainability and state building that is part of the wider strategic agenda. There will also be a climate change mitigation component (ICF) within the programme.

Programme Id GB-GOV-1-300857
Start date 2022-4-21
Status Implementation
Total budget £113,619,995

Health Resilience Fund in Zimbabwe 2021-2025

UK - Foreign, Commonwealth Development Office (FCDO)

To support a resilient health system in Zimbabwe that is equipped to deliver quality sexual, reproductive, maternal, newborn, child and adolescent health and nutrition services.

Programme Id GB-GOV-1-300816
Start date 2021-12-28
Status Implementation
Total budget £31,775,021

Investing in Human Capital through Partnerships Beyond Aid in the Social Sectors Programme

UK - Foreign, Commonwealth Development Office (FCDO)

To improve governance and accountability in education, health and social protection sectors and contribute to policy and research which will inform interventions to improve equity and reduce poverty.

Programme Id GB-1-203640
Start date 2020-1-22
Status Implementation
Total budget £15,564,900

The Evidence Fund - 300708

UK - Foreign, Commonwealth Development Office (FCDO)

The Evidence Fund procures and manages research and evaluations that primarily benefit ODA eligible countries. Most research and evaluations paid for by the Evidence Fund are country-specific, and all respond to requests for evidence to inform programme or policy decisions. Primarily serving research requests from HMG’s Embassies and High Commissions in ODA eligible countries, and from HMG policy and strategy teams, the Evidence Fund strengthens the evidence behind the UK’s priority international development investments and development diplomacy. The Evidence Fund also invests modest amounts of non-ODA, to strengthen the evidence behind wider UK foreign policy.

Programme Id GB-GOV-1-300708
Start date 2020-7-30
Status Implementation
Total budget £55,118,442

United Kingdom (UK) Support to the Pandemic Fund

UK - Foreign, Commonwealth Development Office (FCDO)

The programme will provide early seed funding towards the Pandemic fund - a new Financial Intermediary Fund for pandemic prevention, preparedness and response hosted by the World Bank

Programme Id GB-GOV-1-301566
Start date 2023-3-13
Status Implementation
Total budget £24,999,999

Asia Regional Trade and Connectivity Programme (ARTCP)

UK - Foreign, Commonwealth Development Office (FCDO)

Increased levels of trade and investment across regions targeted sectors and geographical areas in Central, West and South Asia, with greater access to markets and services for poor people, including women.

Programme Id GB-1-204469
Start date 2018-4-5
Status Implementation
Total budget £31,532,182

Essential Services for Maternal and Child Health [Services Essentiels de Santé Maternelle et Infantile en RDC (SEMI)]

UK - Foreign, Commonwealth Development Office (FCDO)

To support essential maternal, child and infant health services to end preventable deaths in one of the poorest provinces in DRC and strengthen the health system at national and provincial level.

Programme Id GB-GOV-1-301372
Start date 2022-4-22
Status Implementation
Total budget £36,173,950

International Finance Facility for Immunisation

UK - Foreign, Commonwealth Development Office (FCDO)

Reduce vaccine preventable diseases (VPDs) in poor countries in a sustainable way using innovative financing approach

Programme Id GB-1-111073
Start date 2007-4-10
Status Implementation
Total budget £1,361,550,431

Tackling Deadly Diseases in Africa Programme 2

UK - Foreign, Commonwealth Development Office (FCDO)

The Tackling Deadly Diseases in Africa 2 (TDDAP 2) programme will help implement the UK’s vision for progress on health security in Africa. It will provide technical and financial support to build health security capacity in up to 5 selected countries, including middle ground powers, strengthen key regional bodies such as the Africa Centre for Disease Control and establish long-term partnerships between African, UK and global institutions. Outcomes; • Strengthened regional institutions to help build and improve global health security; • Improved national public health systems and functions with increased national ownership and leadership of outbreak responses; • Communities trained and provided with the knowledge and tools to identify risks and respond to outbreaks; • An emergency response/contingency mechanism to enable the UK to quickly respond to disease outbreaks and help prevent these from escalating to crisis; • Independent monitoring and evaluation component

Programme Id GB-GOV-1-300585
Start date 2023-5-25
Status Implementation
Total budget £95,349,019

Evidence for Health - E4H

UK - Foreign, Commonwealth Development Office (FCDO)

This programme builds on earlier UK investments in Pakistan. It will strengthen the ability of Pakistan’s health system to recover from COVID-19 pandemic as well as building resilience for future pandemics. It will strengthen evidence-based decision making in the health sector and support the implementation of Universal Health Coverage (UHC) and build climate resilient health systems including for vulnerable communities. It will focus technical assistance on the provincial governments of Punjab and Khyber Pakhtunkhwa (KP), with support for the Federal government as well support flood recovery.

Programme Id GB-GOV-1-300801
Start date 2022-1-14
Status Implementation
Total budget £34,987,391

Humanitarian Assistance and Resilience Building in Somalia (HARBS) 2022-2028

UK - Foreign, Commonwealth Development Office (FCDO)

To meet the most urgent humanitarian needs of conflict and disaster affected populations through provision of life-saving assistance and contribute to resilience building of benefitting households to withstand shocks.

Programme Id GB-GOV-1-300978
Start date 2022-8-7
Status Implementation
Total budget £330,758,156

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