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Fleming Fund - The Commonwealth Partnerships for Antimicrobial Stewardship (CwPAMS) Programme
UK - Department of Health and Social Care (DHSC)
This is an Official Development Assistance (ODA) funded UKaid project from the Department of Health and Social Care (DHSC)’s Fleming Fund which helps to fight antimicrobial resistance (AMR) in low- and middle-income countries (LMICs) where the burden of drug-resistant infection is greater. This is a health partnership programme to improve antimicrobial stewardship across Zambia, Tanzania, Ghana, Uganda, Sierra Leone, Kenya, Malawi and Nigeria. The partnerships leverage the expertise of UK health institutions and technical experts to strengthen the capacity of the national health workforce and institutions in partner countries to address AMR challenges. The project aims to: (1) Develop partnerships between NHS Trusts (hospitals) and clinics/hospitals in LMIC Commonwealth countries; (2) Share UK expertise abroad as well as bring skills and knowledge back to NHS Trusts; (3) Create focused partnerships on the theme of AMR, that includes activity on: Antimicrobial stewardship, including surveillance (AMS); Infection prevention control; and antimicrobial pharmacy expertise and capacity; and (4) More generally improve the knowledge, skills and empowerment of healthcare professionals and pharmacists in partner institutions, thus enabling the healthcare workforce to ultimately contribute to a strengthened health system. This project was not put out to an open, competitive tender process because the implementing partners were assessed as having a unique model of skills exchange and volunteer deployment tailored to antimicrobial stewardship in low- and middle-income countries, but with strong ties to the UK, allowing for skills exchanges and ongoing virtual partnerships. This was not replicated by any other organisation at the time of award.
Fleming Fund - Senegal Country Grant (FAO) Animal Health
UK - Department of Health and Social Care (DHSC)
This is an Official Development Assistance (ODA) funded UKaid project from the Department of Health and Social Care (DHSC)’s Fleming Fund which helps to fight antimicrobial resistance (AMR) in low- and middle-income countries (LMICs) where the burden of drug-resistant infection is greater. This grant is delivered by the Food and Agriculture Organization of the United Nations (FAO) and managed by the Fleming Fund management agent as part of the wider portfolio of country, regional and fellowship grants. The grant aims to develop the foundations for AMR and Antimicrobial Use (AMU) surveillance in the animal health sector and some aspects of AMR surveillance in the environment. Its primary objectives are to: (1) Strengthen One Health* governance and data sharing; and (2) Strengthen the AMR and AMU surveillance systems in animal and environmental health. (*One Health is an integrated, unifying approach that aims to sustainably balance and optimise the health of people, animals and ecosystems. It recognises that the health of humans, domestic and wild animals, plants, and the wider environment (including ecosystems) are closely linked and interdependent.) See ‘Fleming Fund - Country and Regional Grants and Fellowships Programme’ GB-GOV-10-FF_MA for more information on the objectives of country grants. This project was not put out to an open, competitive tender process because the Fleming Fund Managing Agent identified this implementing partner as uniquely placed to undertake project delivery. However, UN policy states that commercial agreements must be MoUs and must be signed with participating countries. As such, DHSC facilitated the signing of commercial agreements for downstream partners of the Management Agent where appropriate.
Fleming Fund - Website Development and Maintenance
UK - Department of Health and Social Care (DHSC)
This is an Official Development Assistance (ODA) funded UKaid project from the Department of Health and Social Care (DHSC)’s Fleming Fund which helps to fight antimicrobial resistance (AMR) in low- and middle-income countries (LMICs) where the burden of drug-resistant infection is greater. This contract supports the hosting and maintenance of the Fleming Fund website, an external-facing sites that hosts information on Fleming Fund country, regional, and global grants and the fellowship scheme. The website supports the Fund to raise awareness of AMR in LMICs and reflects the breadth of the Fund’s work. It supports the communication and sharing of programme information including publications, news articles, and funding announcements. The website is an integral part of the Fleming Fund’s wider communications strategy. The first supplier was procured through an open, competitive process. The second supplier was contracted using a direct award via the government Crown Commercial Service which offers better value for money and beneficial terms to government agencies for off the shelf solutions.
Fleming Fund - Multilateral Grant to the World Health Organization (WHO) - Antimicrobial Resistance Quadripartite
UK - Department of Health and Social Care (DHSC)
This is an Official Development Assistance (ODA) funded UKaid project from the Department of Health and Social Care (DHSC)’s Fleming Fund which helps to fight antimicrobial resistance (AMR) in low- and middle-income countries (LMICs) where the burden of drug-resistant infection is greater. This grant is a contribution to the World Health Organization (WHO) to support countries to implement AMR National Action Plans (NAP) and the development of global protocols for collection of AMR data. The grant objectives are to: (1) Support countries in the Fleming Fund’s regional focus areas of Sub-Saharan Africa, South and Southeast Asia to develop NAPs; (2) Develop a One Health* AMR surveillance protocol focused on Escherichia coli (E. coli); (3) Develop, pilot and roll out methods for monitoring antibiotic consumption and use; (4) Develop and support countries to implement new classification of antibiotics within the Essential Medicines List (EML) and the AWaRe categorisation to encourage rational use of antibiotics; (5) and (6) Strengthen coordination across the UN AMR Quadripartite (WHO, the Food and Agriculture Organization of the United Nations (FAO), the World Organisation for Animal Health (WOAH), and the United Nations Environment Programme (UNEP)) to support the One Health* agenda globally, and specifically in LMICs. (*One Health is an integrated, unifying approach that aims to sustainably balance and optimise the health of people, animals and ecosystems. It recognises that the health of humans, domestic and wild animals, plants, and the wider environment (including ecosystems) are closely linked and interdependent.) This project was not put out to an open, competitive tender process because these UN agencies are the only existing organisations in the world with a global mandate to work on AMR with their level of influence and reach. WHO has a unique mandate on human health and coordinates AMR and health workforce plans at regional and country level (something that no other organisation is able to do). FAO is uniquely placed to contribute to the international efforts to address AMR and to provide support to governments, producers, traders, and other stakeholders to adopt measures to minimise the use of antimicrobials and to reduce AMR, while also sensitive to the needs of the food and agriculture sector worldwide. WOAH is the intergovernmental organisation responsible for improving animal health and welfare worldwide.
Fleming Fund - Multilateral Grant to the World Health Organization (WHO) - Substandard and Falsified Medicines (SF)
UK - Department of Health and Social Care (DHSC)
This is an Official Development Assistance (ODA) funded UKaid project from the Department of Health and Social Care (DHSC)’s Fleming Fund which helps to fight antimicrobial resistance (AMR) in low- and middle-income countries (LMICs) where the burden of drug-resistant infection is greater. It is delivered in partnership with the World Health Organization (WHO) and focuses on increasing the use of data on substandard and falsified (SF) medicines to tackle AMR and support sustainable policies and solutions at both national and regional levels. This ‘Data for Action’ directly supports LMICs to collect data to facilitate the Prevention, Detection and Response to Substandard and Falsified Antimicrobial Medical Products through increasing the quality and quantity of data and analysis. The project also strengthens coordination with the World Organisation for Animal Health (WOAH) and other partners to support learning across human and veterinary medical products on the detection and identification of substandard and falsified medicines. This project was not put out to an open, competitive tender process because these UN agencies are the only existing organisations in the world with a global mandate to work on AMR with their level of influence and reach. WHO has a unique mandate on human health and coordinates AMR and health workforce plans at regional and country level (something that no other organisation is able to do). FAO is uniquely placed to contribute to the international efforts to address AMR and to provide support to governments, producers, traders, and other stakeholders to adopt measures to minimise the use of antimicrobials and to reduce AMR, while also sensitive to the needs of the food and agriculture sector worldwide. WOAH is the intergovernmental organisation responsible for improving animal health and welfare worldwide.
Fleming Fund - Caribbean Antimicrobial Resistance Alliance (CARA) Project (UKHSA and CARPHA)
UK - Department of Health and Social Care (DHSC)
This is an Official Development Assistance (ODA) funded UKaid project from the Department of Health and Social Care (DHSC)’s Fleming Fund which helps to fight antimicrobial resistance (AMR) in low- and middle-income countries (LMICs) where the burden of drug-resistant infection is greater. The Fleming Fund is working with the UK Health Security Agency (UKHSA) to deliver the Caribbean Antimicrobial Resistance Alliance project (CARA) grant in partnership with the Caribbean Public Health Agency (CARPHA). UKHSA will partner with CARPHA to strengthen AMR surveillance, laboratory, and health workforce capacity across its three Regional Reference Laboratories, for the primary benefit of ten ODA-eligible CARPHA Member States. The CARA project also supports a diagnostic AMR solution for Montserrat, an ODA-eligible UK Overseas Territory in the Caribbean. This project was not put out to an open, competitive tender process because UKHSA is an executive agency of DHSC with a mandate to deliver on pandemic preparedness and therefore exempt from the tender process as it is within DHSC’s body of expertise.
Fleming Fund - Sri Lanka Country Grant (WHO) Human Health
UK - Department of Health and Social Care (DHSC)
This is an Official Development Assistance (ODA) funded UKaid project from the Department of Health and Social Care (DHSC)’s Fleming Fund which helps to fight antimicrobial resistance (AMR) in low- and middle-income countries (LMICs) where the burden of drug-resistant infection is greater. This grant is delivered by the World Health Organization (WHO) and managed by the Fleming Fund management agent as part of the wider portfolio of country, regional and fellowship grants. See ‘Fleming Fund - Country and Regional Grants and Fellowships Programme’ GB-GOV-10-FF_MA for more information on the objectives of country grants. This project was not put out to an open, competitive tender process because the Fleming Fund Managing Agent identified this implementing partner as uniquely placed to undertake project delivery. However, UN policy states that commercial agreements must be MoUs and must be signed with participating countries. As such, DHSC facilitated the signing of commercial agreements for downstream partners of the Management Agent where appropriate.
Fleming Fund
UK - Department of Health and Social Care (DHSC)
The Fleming Fund is a £265m commitment of Official Development Assistance (ODA) from the UK Department of Health and Social Care (DHSC) by the UK Government to help fight antimicrobial resistance (AMR) in low- and middle-income countries (LMICs) where the burden of drug-resistant infection is greater. Information about individual Fleming Fund projects and contracts can be found under the ‘child activities linked to this activity. The Fleming Fund aims to: (1) Support the development of National Action Plans for AMR; (2) Develop and support the implementation of protocols and guidance for AMR surveillance and antimicrobial use; (3) Build sustainable laboratory capacity for AMR sensitivity testing and diagnosis; (4) Build sustainable drug resistance surveillance capacity and networks; (5) Enable the sharing of drug resistance data locally, regionally and nationally; (6) Facilitate the increased use of drug resistance data to monitor and address resistance as it evolves; and (7) Advocate for the application of data to promote the rational use of antimicrobials for human health, animal health and agriculture.
Global Antimicrobial Resistance Innovation Fund (GAMRIF)
UK - Department of Health and Social Care (DHSC)
The Global Antimicrobial Resistance Innovation Fund (GAMRIF) is an Official Development Assistance (ODA) funded UKaid programme from the Department of Health and Social Care (DHSC). It supports high-quality research and development (R&D) around the world to reduce the threat of antimicrobial resistance (AMR) in humans, animals, and the environment for the benefit of people in low- and middle-income countries (LMICs), focussing on product development (such as therapeutics, alternatives, vaccines, diagnostics and beyond). GAMRIF delivers through bilateral partnerships, global initiatives, and product development partnerships (PDPs) to establish international research partnerships with industry, academia, and governments. This approach enables it to collaborate with, and leverage additional funding from, other global donors to develop innovative One Health* solutions to tackle AMR in LMICs and increase the availability of context-specific, accessible, and affordable innovations for LMICs. (*One Health is an integrated, unifying approach that aims to sustainably balance and optimise the health of people, animals and ecosystems. It recognises that the health of humans, domestic and wild animals, plants, and the wider environment (including ecosystems) are closely linked and interdependent.)
Global Antimicrobial Resistance Innovation Fund (GAMRIF) - Programme Costs
UK - Department of Health and Social Care (DHSC)
This is an Official Development Assistance (ODA) funded UKaid project from the Department of Health and Social Care (DHSC)’s Global Antimicrobial Resistance Innovation Fund (GAMRIF). GAMRIF funds research and development to fight antimicrobial resistance (AMR) in low- and middle-income countries (LMICs) where the burden of drug-resistant infection is greater. Programme costs support the running of the programme through additional activity, such as events with delivery partners or Monitoring, Evaluation and Learning (MEL) resources.
International Health Regulations Strengthening Project (IHR-SP)
UK - Department of Health and Social Care (DHSC)
This is an Official Development Assistance (ODA) funded UKaid project from the Department of Health and Social Care (DHSC). The International Health Regulations Strengthening Project (IHR-SP) provides peer to peer technical expertise, delivered through the UK Health Security Agency (UKHSA, formerly Public Health England (PHE)), to support ODA-eligible public health partners in low- and middle-income countries (LMICs) to prepare, prevent, detect and respond to global health threats and increase compliance with the International Health Regulations (IHR), 2005. IHR-SP works bilaterally with four priority partner countries (Nigeria, Pakistan, Ethiopia, and Zambia) and three regions (Africa (primarily through Africa CDC), the Eastern Mediterranean, and Southeast Asia). These partnerships reduce the impact of public health emergencies and enhance partner countries' health security, and in turn, global health security. Activities are based on requests from partner countries, in partnership with National Public Health Institutes, Ministries of Health, and regional organisations, etc. To achieve its aims, the IHR-SP works with public health institutions in priority countries, with assessed need for improved IHR capacity and capability and significant UK links and diaspora. They work with regional bodies, such as Africa CDC, where there is also the potential to amplify the impact of our investment. The project focuses on three key priority areas: (1) Build technical capabilities of public health institutions and public health bodies; (2) Strengthen leadership and management capabilities, as well as support workforce development of partner countries and organisations; and (3) Further develop sustainable resilient public health systems and networks. This project was not put out to an open, competitive tender process because UKHSA is an executive agency of DHSC with a mandate to deliver on pandemic preparedness and therefore exempt from the tender process as it is within DHSC’s body of expertise.
Fleming Fund - Sierra Leone Country Grant (WHO) Human Health
UK - Department of Health and Social Care (DHSC)
This is an Official Development Assistance (ODA) funded UKaid project from the Department of Health and Social Care (DHSC)’s Fleming Fund which helps to fight antimicrobial resistance (AMR) in low- and middle-income countries (LMICs) where the burden of drug-resistant infection is greater. This grant is delivered by the World Health Organization (WHO) and managed by the Fleming Fund management agent as part of the wider portfolio of country, regional and fellowship grants. The grant aims to develop a robust AMR diagnostic stewardship programme in Sierra Leone, increasing the data collected, analysed, and used. At the national level, it will integrate AMR surveillance into other areas of work at sector and integrated surveillance levels. Efforts will be made to increase health workforce capacity to perform advanced microbiology testing techniques. In addition, coordination will be strengthened following One Health* principles, and practitioner engagement and policy initiatives will be implemented to encourage the use of AMR data. (*One Health is an integrated, unifying approach that aims to sustainably balance and optimise the health of people, animals and ecosystems. It recognises that the health of humans, domestic and wild animals, plants, and the wider environment (including ecosystems) are closely linked and interdependent.) See ‘Fleming Fund - Country and Regional Grants and Fellowships Programme’ GB-GOV-10-FF_MA for more information on the objectives of country grants. This project was not put out to an open, competitive tender process because the Fleming Fund Managing Agent identified this implementing partner as uniquely placed to undertake project delivery. However, UN policy states that commercial agreements must be MoUs and must be signed with participating countries. As such, DHSC facilitated the signing of commercial agreements for downstream partners of the Management Agent where appropriate.
Fleming Fund - Antimicrobial Resistance (AMR) Secondments
UK - Department of Health and Social Care (DHSC)
This is an Official Development Assistance (ODA) funded UKaid project from the Department of Health and Social Care (DHSC)’s Fleming Fund which helps to fight antimicrobial resistance (AMR) in low- and middle-income countries (LMICs) where the burden of drug-resistant infection is greater. This scheme supports the secondment of AMR experts to multilateral organisations. Previous secondees have worked in the World Health Organization (WHO), the Food and Agriculture Organisation of the United Nations (FAO) and the World Organisation for Animal Health (WOAH) supporting collaborative working across the UN AMR Quadripartite (FAO, WOAH, WHO and the United Nations Environment Programme (UNEP)). This project was not put out to an open, competitive tender process because the Veterinary Medicines Directorate, who manage the Secondments, is a non-departmental public body of the UK government and therefore exempt from the tender process as it is within DHSC’s body of expertise.
Fleming Fund - Support for Tackling Antimicrobial Resistance in Low- and Middle-Income Countries (South Centre)
UK - Department of Health and Social Care (DHSC)
This is an Official Development Assistance (ODA) funded UKaid project from the Department of Health and Social Care (DHSC)’s Fleming Fund which helps to fight antimicrobial resistance (AMR) in low- and middle-income countries (LMICs) where the burden of drug-resistant infection is greater. This project is delivered in partnership with the South Centre and aims to: (1) Increase awareness of AMR among high-level officials and key stakeholders in LMICs; (2) Support civil society organisations (CSOs) to engage, build capacity and increase awareness of AMR, and advocate for action in government and the private sector; (3) Foster exchange and learning on AMR National Action Plan (NAP) implementation; and (4) Undertake activities in collaboration with the Food and Agriculture Organization of the United Nations (FAO), the United Nations Environment Programme (UNEP), the World Organisation for Animal Health (WOAH) and the World Health Organization (WHO) and other relevant agencies at international and regional levels to support more collaboration and coordinated support on AMR, and better use of resources. This project was not put out to an open, competitive tender process because the South Centre is unique as an intergovernmental organisation focused only on helping low- and middle-income countries (LMICs) – one of the only organisations made for LMICs, by LMICs. It has extensive policy expertise within AMR and is uniquely placed to influence government decisions through collaboration between LMICs.
WHO as a facilitator for equitable clinical trial capacity in low resourced settings
UK - Department of Health and Social Care (DHSC)
The UK Department of Health and Social Care (DHSC) funds outstanding global health research through the National Institute for Health and Care Research (NIHR). DHSC is supporting the World Health Organization (WHO) between 2024-2026 to implement the World Health Assembly Clinical Trials Resolution with a focus on low and middle-income country (LMIC) settings. Intended impact is to deliver good practice guidelines to implement the WHA Resolution and improve capability and quality of clinical trials in particular in LMIC settings, including increasing participation by under-represented groups and improving ethical considerations.
Fleming Fund - Multilateral Grant to the Food and Agriculture Organization of the United Nations (FAO)
UK - Department of Health and Social Care (DHSC)
This is an Official Development Assistance (ODA) funded UKaid project from the Department of Health and Social Care (DHSC)’s Fleming Fund which helps to fight antimicrobial resistance (AMR) in low- and middle-income countries (LMICs) where the burden of drug-resistant infection is greater. This is a grant to the Food and Agriculture Organization of the United Nations (FAO) to: (1) Support development and implementation of AMR National Action Plans in 12 LMICs in sub-Saharan Africa and South and Southeast Asia; (2) Strengthen regulatory frameworks; (3) Increase societal awareness and understanding of AMR; (4) Develop good practices in food and agriculture sectors, and ensure these are able to be implemented in target countries; and (5) Strengthen coordination between FAO, the World Health Organization (WHO), the United Nations Environment Programme (UNEP) and the World Organisation for Animal Health (WOAH) in supporting the One Health* agenda globally, and more specifically in LMICs. (*One Health is an integrated, unifying approach that aims to sustainably balance and optimise the health of people, animals and ecosystems. It recognises that the health of humans, domestic and wild animals, plants, and the wider environment (including ecosystems) are closely linked and interdependent.) This project was not put out to an open, competitive tender process because these UN agencies are the only existing organisations in the world with a global mandate to work on AMR with their level of influence and reach. WHO has a unique mandate on human health and coordinates AMR and health workforce plans at regional and country level (something that no other organisation is able to do). FAO is uniquely placed to contribute to the international efforts to address AMR and to provide support to governments, producers, traders, and other stakeholders to adopt measures to minimise the use of antimicrobials and to reduce AMR, while also sensitive to the needs of the food and agriculture sector worldwide. WOAH is the intergovernmental organisation responsible for improving animal health and welfare worldwide.
Global Health Workforce Programme - Global Health Partnerships (GHP)
UK - Department of Health and Social Care (DHSC)
This is an Official Development Assistance (ODA) funded UKaid project from the Department of Health and Social Care (DHSC)'s Global Health Workforce Programme which provides strategic support to optimise, build and strengthen the health workforce in low- and middle-income countries (LMICs), enabling them to build stronger and more resilient health systems for health security, and to make progress towards universal health coverage. This project is delivered in partnership with Global Health Partnerships (GHP) (formerly the Tropical Health and Education Trust (THET)) to set up and deliver health partnerships between UK and in-country institutions in Kenya, Nigeria, Ghana, Ethiopia, Malawi and Somaliland.
Global Health Workforce Programme - World Health Organization (WHO)
UK - Department of Health and Social Care (DHSC)
This is an Official Development Assistance (ODA) funded UKaid project from the Department of Health and Social Care (DHSC)'s Global Health Workforce Programme which provides strategic support to optimise, build and strengthen the health workforce in low- and middle-income countries (LMICs), enabling them to build stronger and more resilient health systems for health security, and to make progress towards universal health coverage. This project is delivered in partnership with the World Health Organization (WHO) to optimise the health workforces in Ghana, Kenya and Nigeria through improved workforce planning, policies, data and management. The programme also supports the WHO/ILO*/OECD** Working for Health Multi-Partner Trust Fund, which provides financial and technical support to improve health workforces and work towards achieving universal health coverage. (*International Labour Organization; **Organisation for Economic Cooperation and Development). This project was not put out to an open, competitive tender process because WHO has a unique mandate on human health and coordinates health workforce plans at regional and country level (something that no other organisation is able to do).
Fleming Fund - Independent Evaluation
UK - Department of Health and Social Care (DHSC)
This is an Official Development Assistance (ODA) funded UKaid project from the Department of Health and Social Care (DHSC) to independently evaluate its Fleming Fund which helps to fight antimicrobial resistance (AMR) in low- and middle-income countries (LMICs) where the burden of drug-resistant infection is greater. The independent evaluation will assess how far the outputs of the portfolio of country, regional, and global grants, and the Fleming Fellowships, contribute to the outcomes and impact identified by DHSC. Six specific questions were agreed during the inception phase for the evaluation and in answering these, the evaluation intends to meet three objectives: (1) In 2019, the evaluation will generate learning to inform course correction and adaptation in phase 1; (2) In late 2020, the evaluation’s focus will shift to providing an independent summative judgement of the Fund’s results and achievements in phase 1; (3) At the end of phase 2 the evaluation will provide an independent summative judgement of the Fund’s results and achievements in phase 2.
Fleming Fund - Country and Regional Grants and Fellowships Programme
UK - Department of Health and Social Care (DHSC)
This is an Official Development Assistance (ODA) funded UKaid project from the Department of Health and Social Care (DHSC)’s Fleming Fund which helps to fight antimicrobial resistance (AMR) in low- and middle-income countries (LMICs) where the burden of drug-resistant infection is greater. A management agent, Mott MacDonald, has been appointed to deliver: (1) Country grants across up to 25 LMICs; (2) Regional grants in West Africa, East and Southern Africa, South Asia and Southeast Asia; (3) Global projects; and (4) A fellowships programme. These initiatives aim to improve laboratory capacity and diagnosis, data generation and use, and strengthen AMR surveillance systems. Through the country, regional and strategic grants, and the fellowships programme the Fleming Fund will: (1) Build laboratory capacity for diagnosis; (2) Collect data on drug resistance, drug quality, drug use and the burden of disease associated with AMR; (3) Enable the sharing of data relevant to AMR locally, regionally, and internationally; (4) Encourage the application of data to promote the rational use of antimicrobials; (5) Shape a sustainable system for AMR surveillance and data sharing; and (5) Increase national leadership in addressing AMR.
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