Go to main content

FCDO ODA allocations for 2021/22 were announced on 21 April 2021. Changes to individual programmes are underway. The information on this website may not reflect the latest allocated budgets for this year. This information will be updated in due course.

UK aid from the British people
  1. Home
  2. Search Results

Search Results for: "Wellcome Trust Sanger Institute"

Sort results by: Title
Default filter shows currently active projects. To see projects at other stages, use the status filters.
Now showing projects 7 of 7

NIHR Global Health Research Units and Groups: research call 1

UK - Department of Health and Social Care (DHSC)

1) Deliver the UK's ambition to be internationally outstanding in global health research, improving the lives of people in LMICs. 2) Create an environment where world-class global health research, focused on the needs of LMICs can thrive. 3) Translate advances in applied global health research into benefits for patients and the public in LMICs. 4) Focus on priority areas which will have the greatest impact on health in LMICs in the short, medium and long term. 5) Provide high quality research evidence to inform decision-making by public health officials, practitioners and policy makers. 6) Increase the volume and quality of multi-disciplinary global health research from the UK. 7) Develop knowledge and capacity within existing UK institutions which can be translated into global health research practice. 8) Retain a level of responsive research capacity to address emerging global health research requirements (Units only).

Project Identifier:
GB-GOV-10-NIHR_GHRUG1
Activity Status:
Implementation
Start Date:
01-04-2017
Total Budget:
£130,820,088


NIHR Global Health Research Groups: research call 2

UK - Department of Health and Social Care (DHSC)

1) Deliver the UK's ambition to be internationally outstanding in global health research, improving the lives of people in LMIC. 2) Create an environment where world-class global health research, focused on the needs of LMIC can thrive. 3) Translate advances in applied global health research into benefits for patients and the public in LMIC. 4) Focus on priority areas which will have the greatest impact on health in LMIC in the short, medium and long term. 5) Provide high quality research evidence to inform decision-making by public health officials, practitioners and policy makers. 6) Increase the volume and quality of multi-disciplinary global health research from the UK. 7) Develop knowledge and capacity within existing UK institutions which can be translated into global health research practice.

Project Identifier:
GB-GOV-10-NIHR_GHRG2
Activity Status:
Implementation
Start Date:
01-04-2018
Total Budget:
£43,753,616


Using single-cell RNAseq to investigate human malaria parasite transmission dynamics

UK - Department for Business, Energy and Industrial Strategy

Document individual parasite transcriptional patterns and different developmental stages in vivo for three species of wild human malaria parasite. Sequence > 300,000 individual P. falciparum parasite transcriptomes generated from samples taken from 50 symptomatic and 50 asymptomatic carriers. Use these data to build a "Malaria Cell Atlas", a data repository with expression information on every gene across every cell, with interactive visual options (see our current website). Ensure the "Malaria Cell Atlas" is easily accessible and fully open access for both small and large queries from a range of users (academics to pharmaceutical industry). Use genetic relatedness to measure the relationships between asexual and sexual parasites within hosts and whether this differs between symptomatic and asymptomatic hosts. Understand intra- and inter-host variation in parasite transcriptomes and how this relates to symptoms. Determine the repertoire of different parasite cell types present in natural carriers of three species of human malaria. Document patterns of multigene family expression and sexual development in P. malariae and P. ovale for the first time. Develop methods supporting field deployment of single cell transcriptomics in a low resource setting. Develop methods allowing multiplexing of malaria single cell transcriptomics by cell hashing. Use genetic variation present in RNAseq reads from single cell transcriptomes to assign a genotype to each individual parasite. Expose mosquitoes to the same parasites present in the deeply interrogated 300K/100 donor cell set. Use single cell sequencing to understand how gametocyte genetic diversity is represented in the next generation's transmitted sporozoite population.

Project Identifier:
GB-GOV-13-FUND--GCRF-MR_S02445X_1
Activity Status:
Implementation
Start Date:
02-10-2019
Total Budget:
£345,387


Identifying the drivers and vulnerabilities of acral lentiginous melanoma through the study of PDX models from Latin American patients

UK - Department for Business, Energy and Industrial Strategy

General: To identify the genomic drivers, including genetic risk factors, and vulnerabilities of acral lentiginous melanoma. Specific: 1. To generate and characterise an ALM patient-derived xenograft (PDX) platform from Latin American patients. 2. To use the established ALM-PDX platform to identify and explore genetic risk factors, potential therapeutically targetable alterations and disease biomarkers.

Project Identifier:
GB-GOV-13-FUND--GCRF-MR_S01473X_1
Activity Status:
Implementation
Start Date:
15-11-2018
Total Budget:
£188,804


Mechanism-guided drug repurposing to accelerate the development of novel therapies for oral squamous cell carcinoma (OSCC)

UK - Department for Business, Energy and Industrial Strategy

1. To build a comprehensive reference of drug repurposing opportunities in OSCC by performing high-throughput drug screening on a unique collection of highly genomically annotated OSCC cell lines derived from Asians; 2. To integrate drug response data with multi-omics and gene essentiality data to guide the identification of selective drugs with delineation of the mechanism of action; 3. To identify biomarkers for prediction of drug response in patients for future clinical studies

Project Identifier:
GB-GOV-13-FUND--Newton-MR_V005936_1
Activity Status:
Implementation
Start Date:
12-06-2020
Total Budget:
£71,448


Project Identifier:
GB-COH-RC000346-G0501670/2
Activity Status:
Implementation
Start Date:
N/A
Total Budget:
Budget: Not Provided


Project Identifier:
GB-COH-RC000346-MR/J002283/1
Activity Status:
Implementation
Start Date:
N/A
Total Budget:
Budget: Not Provided


Results Filter

Status

Activity Status

Locations

+

Countries

+

Regions

Sectors

Sectors
+

Organisations

Implementing Organisations

Implementing Organisations

Start and end date

This site uses cookies

We use Google Analytics to measure how you use the website so we can improve it based on user needs. Google Analytics sets cookies that store anonymised information about how you got to the site, the internal pages you visit, how long you spend on each page and what you click on while you're visiting the site. Read more