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Development of Triple Artemisinin-based Combination Therapies
The University of Oxford
The goal of the Development of Triple Artemisinin-based Combination Therapies (DeTACT) project is to provide a solution using currently available antimalarials to contain multidrug-resistant Plasmodium falciparum malaria in the Greater Mekong Sub region, and to prevent the spread or emergence of resistance in India, Africa, and beyond. DeTACT aims to provide evidence from clinical, market and community-based research in support of a global change in policy to allow large-scale deployment of triple artemisinin-based combination therapies (TACTs) for the treatment of uncomplicated Plasmodium falciparum malaria. Switching from artemisinin-based combination therapies (ACTs) to TACTs could be one of the last available options using currently available drugs to treat multidrug-resistant falciparum malaria and prevent or delay it from spreading or emerging in areas where it is not yet present. The project is divided into six work packages: (1) Develop two co-packaged TACTs for uncomplicated P. falciparum malaria. (2) Using these products, conduct randomised, controlled, non-inferiority trials in 13 sites in 8 African countries and 4 Asian countries to provide evidence of safety, tolerability, and efficacy of the TACTs. (3) Mathematical modelling to assess the potential of TACTs to delay the emergence and further spread of antimalarial drug resistance and the costs and benefits of introducing TACTs in countries with different levels of drug resistance, malaria transmission rates, and adherence to treatment guidelines. (4) Analyse the conceptual ethical aspects and conduct an empirical ethics/social science study addressing the ethical aspects of a change to TACTs in the African paediatric patient population. (5) A market positioning assessment based on interviews and focus group discussions with stakeholders ranging from end users to national and regional policy makers, to address the barriers and strategies to overcome these, and acceptability of changing to TACTs in Asia and Africa, which present different epidemiological settings. (6) Effective communication of the design of the study and evidence generated in order to engage with key stakeholders at an early stage.
Programme identifier:
GB-UKPRN-10007774-DeTACT
Start Date:
2018-07-16
Activity Status:
Implementation
Total Budget:
£9,227,166
Centre of Excellence for Development Impact and Learning (CEDIL)- Programme Directorate
Oxford Policy Management
The CEDIL Programme Directorate will manage and implement the vision and evaluation research agenda of CEDIL, ensuring the delivery of a large, high profile, international centre that will develop impact evaluation research capacity within the UK and internationally.
Programme identifier:
GB-COH-03122495-A2012
Start Date:
2018-04-16
Activity Status:
Implementation
Total Budget:
£8,016,228
Understanding opportunities for mainstreaming climate actions within urban planning
Oxford Policy Management
OPM is conducting a study on behalf of the Foreign and Commonwealth Development Office (FCDO), Government of United Kingdom (UK) to understand the opportunities to mainstream climate actions in urban planning processes in Indian cities. The study involves a lierature review and key informant consultations.
Programme identifier:
GB-COH-03122495-A5112
Start Date:
2022-02-23
Activity Status:
Implementation
Total Budget:
£65,730
Women's Integrated Sexual Health (WISH) Third-Party Monitoring
Oxford Policy Management
The Women’s Integrated Sexual Health (WISH) programme is FCDO’s flagship sexual and reproductive health (SRH) programme. This £238 million programme, operating in 27 countries in sub-Saharan Africa and Asia over a period of three years, will deliver up to 20% of the UK’s overall commitment to improving global sexual and reproductive health and rights by ensuring equitable access to family planning, and sexual and reproductive health services to women and girls across the global, particularly the vulnerable and marginalised populations. We, in partnership with Itad, conduct monitoring of WISH results and support for evidence and learnings to provide FCDO with updates on programme impact and to inform programme adaptation to maximise performance.
Programme identifier:
GB-COH-03122495-A2119
Start Date:
2018-08-16
Activity Status:
Implementation
Total Budget:
£2,925,000
Climate commitments and public finance - Linkages and potential for synergy
Oxford Policy Management
This is a short study on the links between NDCs (and broader climate policy) and issues of public finance, notably national budgets, and tax and expenditure policies – focusing on 10 countries in South and South-East Asia. Given that domestic budgets of countries could play a significant role in furthering climate action, the study will add to the evidence around how these could be best synergized with direct climate finance commitments to achieve stronger climate benefits. Following a desk review, the study will gather key stakeholder perspectives to substantiate the identified synergies, leading to country-specific analyses and a final virtual dissemination event.
Programme identifier:
GB-COH-03122495-A5068
Start Date:
2022-01-27
Activity Status:
Implementation
Total Budget:
£79,060
The Evaluation of Phase Three of the Hunger Safety Net Programme (HSNP) 3
Oxford Policy Management
This project delivers the Monitoring, Evaluation and Knowledge (MEK) component of HSNP Phase 3. The first (Monitoring) and second (Capacity Assessment) workstreams of the MEK contract are focused on providing technical assistance and support to the National Drought Management Authority (NDMA) as they take over the management and implementation of the HSNP in its third phase. The third (Process Review) and fourth (Impact Evaluations) workstreams are focussed on providing an assessment of the economic inclusion programme pilots, which are being implemented by the Department for Social Development (DSD) as part of the World Bank’s Kenya Social Economic Inclusion Programme (KSEIP). In addition, there is budget for ‘deep dive’ studies which are allocated flexibly and designed to be responsive to emergent needs.
Programme identifier:
GB-COH-03122495-A3967
Start Date:
2019-12-02
Activity Status:
Implementation
Total Budget:
£1,977,605
Epidemiological modelling for public health decision making in sub-Saharan Africa: development of a strategic plan for capacity strengthening
Oxford Policy Management
Development of a strategic plan, through key informant interviews and literature review, to inform donor strategies to support capacity strengthening in epidemiological modelling for countries in sub-Saharan Africa
Programme identifier:
GB-COH-03122495-A4964
Start Date:
2021-10-19
Activity Status:
Implementation
Total Budget:
£49,950
DFID Applied Research on Energy and Economic Growth (EEG)
Oxford Policy Management
This applied research aims to build a body of evidence around how sector reforms, innovative technologies and practicable actions can be used to help maximise the economic impacts of larger scale energy projects in low income countries in Africa and South Asia, and also bring benefits of modern energy services to poorer people.
Programme identifier:
GB-COH-03122495-A0534
Start Date:
2016-04-15
Activity Status:
Implementation
Total Budget:
£12,598,810
Data and Evidence to End Extreme Poverty (DEEP)
Oxford Policy Management
DEEP's vision is that governments, decision makers, and citizens around the globe will have better access to data, tools, and solutions to help end extreme poverty. Over seven years, DEEP's work will influence the design and implementation of policies, strategies, and investments by investigating: Who is living in extreme poverty and how is their situation evolving? What drives extreme poverty? How can we end extreme poverty?
Programme identifier:
GB-COH-03122495-A3290
Start Date:
2020-02-18
Activity Status:
Implementation
Total Budget:
£9,872,003.02
Economic Development & Institutions Research
Oxford Policy Management
Our vision for this programme is a rare combination of cutting-edge rigorous research and innovative policy engagement. This proposal sets out a powerful approach to addressing one of the fundamental challenges of economic development.
Programme identifier:
GB-COH-03122495-A0014
Start Date:
2015-05-01
Activity Status:
Implementation
Total Budget:
£13,783,904.69
Evaluation of African Risk Capacity (ARC) Programme
Oxford Policy Management
The mission of ARC is to use modern finance mechanisms, such as risk pooling and risk transfer, to create pan-African climate response systems that enable African countries to meet the needs of people harmed by natural disasters.
Programme identifier:
GB-COH-03122495-A0603
Start Date:
2015-10-15
Activity Status:
Implementation
Total Budget:
£1,911,290
Performance Evaluation of the Punjab Education Sector Programme (PESP2)
Oxford Policy Management
The Punjab Education Sector Programme (PESP 2) builds on the UK Governments previous support to the Government of Punjab (GoPb), to reform and transform delivery of education in Punjab. It will complement the UK-supported Punjab Education Reform Roadmap.
Programme identifier:
GB-COH-03122495-A2107
Start Date:
2017-08-08
Activity Status:
Implementation
Total Budget:
£1,494,609.27
Policy and Institutions Facility (PIF) - NEPAL
Oxford Policy Management
Nepal is subject to a wide range of disaster risks and impacts, including both earthquakes and climate related hazards. To address these challenges two major new programmes are being initiated, 'Climate Smart Development for Nepal' and 'Strengthening Disaster Resilience in Nepal'.
Programme identifier:
GB-COH-03122495-A1594
Start Date:
2017-08-28
Activity Status:
Implementation
Total Budget:
£3,498,800
Sindh Education Non-State Actors Programme (SENSA) Phase 4
Oxford Policy Management
DFID Pakistan will provide up to £13.3 million for four years to continue funding three of the (I)NGOs previously delivering education to out-of-school children under the intermediary strand of EFS. This is to enable the children enrolled under EFS to complete their primary education, gain quality learning outcomes, and transition to an appropriate next stage.
Programme identifier:
GB-COH-03122495-A2758
Start Date:
2018-08-01
Activity Status:
Implementation
Total Budget:
£950,000
Evaluation of impacts of the Samridhi Fund under the Poorest State Inclusive Growth (PSIG) programme
Oxford Policy Management
The primary objective of the Fund is to promote sustainable enterprises which provide economic, social and/or environmental benefits to the poor in the 8 low income states. The fund seeks to explore the effectiveness of the social venture capital model in promoting pro-poor economic growth. The Fund?s target is to achieve total quantifiable 'socio-economic development' worth ?676 million, in the categories such as increased income from employment, reduction in cost of services used, increase in prices of services offered, increased turnover of investees and additional capital leveraged as well as public goods effects.
Programme identifier:
GB-COH-03122495-8447
Start Date:
2014-02-27
Activity Status:
Implementation
Total Budget:
£999,180.98
Enhancing Diagnostics
Oxford Policy Management
The Inclusive Growth Diagnostic (IGD) exercise was launched to better understand the opportunities and constraints to inclusive growth in our focus countries, regionally and internationally, and to analyse what actions we can take in response to these opportunities and constraints.
Programme identifier:
GB-COH-03122495-A1496
Start Date:
2017-10-10
Activity Status:
Implementation
Total Budget:
£1,572,893.19
Evaluation of Stamping out and Preventing Gender-Based Violence (STOP GBV) Programme, Zambia
Oxford Policy Management
The primary objective of the programme is to improve the prevention and response to gender-based violence, the programme began in 2012 however it is a successor programme to the USAID funded A Safer Zambia (ASAZA) which ran from 2008 to 2011.
Programme identifier:
GB-COH-03122495-A2591
Start Date:
2018-04-16
Activity Status:
Implementation
Total Budget:
£349,017
Employment Led Poverty Reduction in Western Nepal
Oxford Policy Management
To support the Government of Nepal to develop and test new approaches to employment led poverty reduction through pilot projects in two districts in the Karnali Region
Programme identifier:
GB-COH-03122495-A0363
Start Date:
2013-09-09
Activity Status:
Implementation
Total Budget:
£4,785,484.99
Maintaining Essential Services after a Natural Disaster (MAINTAINS)
Oxford Policy Management
In July 2017, DFID approved an investment of up to ?15m over the period 2017-2022 to fund new, operationally-relevant research on how education, health, social protection, nutrition, and water and sanitation services can adapt and expand in response to shocks such as floods, droughts, cyclones and disease outbreaks.
Programme identifier:
GB-COH-03122495-A2241
Start Date:
2018-07-19
Activity Status:
Implementation
Total Budget:
£14,799,995.95
DFID DRC Decision Support Unit (DSU)
Oxford Policy Management
The purpose of the Decision Support Unit is to provide DFID with impartial verification of the results reported by the private sector development programme in the Democratic Republic of Congo (DRC).
Programme identifier:
GB-COH-03122495-A1281
Start Date:
2016-08-08
Activity Status:
Implementation
Total Budget:
£3,482,925