Search Results for: "Bill Gates"
AERAS PRODUCT DEVELOPMENT PARTNERSHIP PROGRAMME 2013 TO 2018: NEW VACCINES FOR TUBERCULOSIS
Tackling global plant and animal health risks which threaten global food systems and health - in partnership with the Bill & Melinda Gates Foundation (BMGF)UK - Foreign, Commonwealth and Development Office (FCDO)
Working in partnership with BMGF to fund a portfolio of agricultural technology investments to secure global food supplies, with a strong focus on tackling global plant health threats through improved data, monitoring and delivery of new technologies in sub-Saharan Africa and South Asia.
The overall objective of the AgResults Initiative is to enhance smallholder welfare and food security for the poor and vulnerable in developing countries through increased investment in agricultural innovation and adoption. It aims to do so by developing financial incentives (i.e. “pull mechanisms”) for private and public sector players to research, develop, and deliver products and services that will improve smallholder agriculture. AgResults consists of a number of pilot projects across the developing world focused on either the adoption of existing technologies or the development and adaptation of new research and technologies. The UK leads on a high quality research and evaluation component.
An increased number of poor people, in particular women and children will receive better quality and more affordable, or free, health services as a result of Non-State Actors (for profit and not for profit private sector, civil society organisations and faith based organisations) playing a more effective role working as part of a health system. This will form part of DFIDs work towards tackling MDG 4 and 5 in particular
This programme will contribute to improved food and nutrition security through effective agriculture interventions and food systems that make nutritous food accessible , acceptable and available to all, particularly woman and young children in poor households.. It includes large-scale studies in Africa and South Asia on the impact and cost effectiveness of agricultural interventions on nutrition and health outcomes, and interdisciplinary studies on the drivers of food choices which influence healthy, safe and nutritious diets.
The Making Country Health Systems Stronger (MCHSS) programme aims to support countries to strengthen their health systems to accelerate progress towards Universal Health Coverage, resulting in more people, specifically the poor and vulnerable, having greater access to essential preventative, curative and rehabilitation health services with increased levels of financial risk protection.
Global Antimicrobial Resistance Innovation Fund (GAMRIF) – Accelerating Antibacterial Innovation with CARB-XUK - Department of Health and Social Care (DHSC)
Projects funded through GAMRIF will primarily benefit people in LMICs, where the burden of drug-resistant infection is greater.
Securing global wheat crops for food and nutritional security - in partnership with the Bill & Melinda Gates Foundation (BMGF)UK - Foreign, Commonwealth and Development Office (FCDO)
Working in partnership with the Bill & Melinda Gates Foundation on two major co-investments in wheat crop improvement, DFID’s funding will increase the nutritional quality and disease resistance of wheat crops, building the resilience of smallholder farmers in Sub-Saharan Africa and South Asia, and contributing to global food security in the face of climate change, and emerging plant disease and pest threats.
This programme will work with the partner governments and the wider development community to improve the collection, management, analysis and use of geospatial and demographic data to improve the lives of the poorest in developing countries. This will allow developing countries and the development community to better understand how many people live where and where key features such as roads, hospitals and schools are located. This improved understanding will enable better planning of public services and targeting of resources.
Sightsavers’ research function focuses on funding research projects across all themes and technical expertise to research and evidence generation
MISSION To be an international resource and centre of excellence for research and capacity building for the epidemiological analysis and modelling of infectious diseases. The Centre has built a world-leading group of epidemiological researchers to undertake applied collaborative work with national and international agencies to support policy planning and response operations against infectious disease threats. STRATEGY AND OBJECTIVES To maintain and strengthen: (a) an international centre for translating new epidemiological analysis and modelling research into practical policy guidance for controlling infectious diseases; (b) a core capacity to respond to emerging threats and time-critical global health research priorities with real-time analysis and predictive modelling; (c) collaborative relationships with national and international public health agencies and facilitate skills transfer and capacity building, including in low and middle income countries (LMICs); (d) an integrated, multidisciplinary research programme to identify the ecological, biological and social determinants of pathogen emergence and spread (e) responsiveness to new priorities for applied intervention research, including assessment of health and economic impact, contributing to vaccine development and evaluation, and addressing the threat posed by antimicrobial resistance. APPROACH Building on 9 years' experience, the Centre core will consist of a shared technical resource (in project management, GIS, database analysis, high-performance computing and professional programming) and a public health stakeholder liaison team. The shared technical resource comprises the Centre scientific manager, a high performance computing technician and two professional software developers. The latter posts are dedicated to improving programming skills and operationalizing the methodological software tools developed by Centre researchers. The liaison team will consist of a research fellow dedicated to our partnership with WHO and an External Relationships and Communications Manager to facilitate capacity-building and research collaborations with external partners (notably, in LMICs) and enhance our external communications. The Centre core will be complemented by investment in capacity building in priority research areas via an expanded PhD programme, a new Imperial-MRC research fellow scheme, five new academic posts and a responsive pump-priming research fund. This structure will allow greater flexibility in responding to new priorities (whether outbreaks or urgent policy questions) and for building and sustaining relationships with a wider range of international partners. RESEARCH THEMES For the next 5 years, Centre research will focus on a set of 5 cross-cutting themes: - Outbreak Analysis and Modelling - Global Health Analytics - Vaccines - Antimicrobial Resistance - Methods and Tools This research will occur in the context of its application to 10 priority disease areas: - Zoonoses and Animal Diseases - HIV, STIs and Hepatitis - Malaria - Tuberculosis - Influenza - Arboviruses - Neglected Tropical Diseases - Enteric Infections - Bacterial Pathogens - Fungal Pathogens The Centre's history of frequent internal as well as external collaboration in both methodological and applied research makes it exceptionally well-placed to deliver this broad, cross-cutting research agenda. Examples of work drawing on expertise from multiple PI groups from the last 5 years include analyses of the MERS-CoV and Ebola epidemics and modelling to inform business planning for the Global Fund. This collaborative culture and the overall coherence of the Centre's research is maintained by regular cross-Centre research meetings, workshops, training programmes and awaydays. Maintaining a high degree of interaction is essential for the Centre to deliver on its mission and objectives,given the highly interdisciplinary research required.
Sightsavers’ function focussing on detailed oversight and management support for significant grant funded projects, ensuring that they are set up, implemented and reported on effectively and with appropriate support from other organisational functions
The overall aim of BactiVac is to establish a bacterial vaccinology network that brings key individuals and organisations together to facilitate end-to-end bacterial vaccine development for low and middle income countries (LMICs) from exploratory research, through clinical trials, to licensure and implementation. No bacterial vaccinology network of this nature presently exists. Therefore, BactiVac will fill a major gap in global vaccinology, providing balance to the current critical mass of vaccinologists converging on outbreak and viral pathogens through the 'UK Vaccines Network', and WHO 'Research and Development Blueprint' and 'Coalition for Epidemic Preparedness Innovations (CEPI)'. BactiVac will draw together entities from the academic, industry and stakeholder sectors from the UK/high income countries (HICs) and LMICs involved in human and animal vaccine R&D to foster partnership, disseminate relevant information and provide catalyst project support with the aim of accelerating LMIC bacterial vaccine development. A particular focus will be to address knowledge gaps in the area, such as identification of bacterial vaccine priorities for LMICs, and to support the transition of vaccines from preclinical to clinical trials, where so many currently flounder. Specific objectives: 1. To establish an open network that connects key individuals and organisations from academia, industry and LMICs to fulfil unmet needs for bacterial vaccines, providing opportunities for the dissemination of knowledge and ideas, fostering partnerships and progressing bacterial vaccine R&D. 2. To establish a framework to address major gaps in our knowledge of bacterial vaccinology, including the prioritisation of LMIC-focused bacterial diseases for vaccine development, and identifying Clinical Research Organisations (CRO), Contract Manufacturing Organisations (CMO) and manufacturing capacities and capabilities to support bacterial vaccine development. 3. To provide support for small-scale projects that will prime substantive funding applications, with an emphasis on those that directly impact bacterial vaccine progression, and involve partnership between network members, particularly members from LMICs and industry. 4. To establish BactiVac as the advocacy network for bacterial vaccinology that campaigns for the need for bacterial vaccines as a means of reducing the burden of endemic bacterial disease, combatting AMR and improving economic development in LMICs. 5. To support training opportunities and exchanges, prioritising those involving LMIC members and industrial partners, for the transfer of knowledge and skills in bacterial vaccinology. 6. To interface with other groups, including other vaccine networks generated from this call, the Developing Countries Manufacturing Network (DCVMN), Veterinary Vaccinology Network (VVN), stakeholder organisation such as WHO and GAVI and funders such as the Bill and Melinda Gates Foundation BMGF) to maximize the reach and use of resources to achieve the network's objectives.
Sightsavers’ strategic evaluations and learning function supports the commission and delivery of robust and meaningful project evaluations to inform our work, improve project design and generate wider learnings
Our aim is to enhance the design, reliability and, ultimately the marketability, of the Asian Institute of Technology (AIT) cess-to-fit system and the solar septic tank. This will be achieved through the following 6 objectives: 1. An ecological survey of 30 full-scale systems that are installed and operated in Thailand will be conducted to determine the characteristics of a well-functioning microbial community and enable correlation of microbial community composition with operational factors. 2. The ecological survey data will be used to contrast that collected during systematic perturbation of full-scale systems operating on the AIT campus to determine the limits of operation and nature of failure in the microbial communities and to enable identification of biological predictors of failure in the system. 3. Pilot-scale trials and failure testing of AIT technologies to determine applicability in the Global North context working at test sites in Scotland identified by industrial partners Scottish Water. 4. Deploying the WASTEBOT to systematically search for a mix of micro-nutrients that will enhance the metabolism of the microbial treatment community and that might be intermittently flushed into the system to promote degradation or applied to mitigate failure in the field. 5. Deploying the WASTEBOT to search for the best mix of inocula to seed a new installation or to remediate a poorly performing one. Delivery of seed sludge might form part of the services provided by the Sanitizer truck. 6. Developing a novel low-cost paper-based pathogen detection kit that can be used for routine monitoring of the treatment process of the technologies in the field and feed data into public health and epidemiological studies on the effectiveness of decentralized wastewater treatment technologies.