CEPI’s vision is a world in which epidemics and pandemics are no longer a threat to humanity. Going into the strategic period from 2022-2026, termed “CEPI 2.0”, CEPI aims to raise the bar to develop and scale vaccines and other promising biologic countermeasures even faster. The R&D community has moved with unprecedented speed in response to COVID-19, developing biological interventions like vaccines and monoclonal antibodies in less than 12 months. While these achievements are historic, what the world needs to avert the consequences of future epidemics and pandemics are countermeasures developed even faster. CEPI’s mission is to accelerate the development of vaccines and other biologic countermeasures against epidemic and pandemic threats so they can be accessible to all people in need. CEPI believes safe and effective vaccine in 100 days from the moment that a pathogen is sequenced and/ or the need for a vaccine is recognised to initial availability for use should be the aspiration. Over the strategic period, CEPI aims to invest USD 3.5 billion across three overall strategic objectives:

1) PREPARE for known epidemic and pandemic threats: End the acute phase of the COVID-19 pandemic by ensuring equitable access to a portfolio of COVID-19 vaccines favourable for LMICs and validate enabling science programmes to accelerate COVID-19 vaccine candidate development. Accelerate the development of vaccines and other biologic countermeasures against known high- risk pathogens, continuing vaccine development towards licensure for priority pathogens with a clear unmet need where vaccines could have an impact. Reduce the risk of further coronavirus pandemics, using the acceleration in vaccine technologies and methods due to COVID-19 response, with the ultimate objective to develop a broadly protective Betacoronavirus vaccine. 2) TRANSFORM the response to the next novel threat: Using vaccine prototypes and platform innovations to give us a head-start on other novel threats. Investing and scaling critical enabling sciences to further accelerate rapid vaccine development. Investing in innovations to ensure vaccine manufacturing is cheaper, faster, and closer to an outbreak. 3) CONNECT to enhance and expand global collaboration: Secure financing for epidemic preparedness and response, connecting countries, industry, public & private sectors from all over the world, and global health partners to develop vaccines and build commitment to preparedness and access. Improve coordination among key stakeholders to enable system readiness, driving for collaboration and solutions which will enable a faster system-wide response. Promote equitable access principles as the foundation of any effective global response.