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UK-SA partnership on Earth Observation for Atmospheric Composition Science (UK-SA EO4ACS)
DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY
Climate change mitigation, and air quality (AQ) improvement are two inter-related pressing global challenges for which high quality, trustable Earth Observation (EO) data are essential. Particularly, quantitative knowledge of atmospheric composition is required to understand the gases and particulates emitted into the atmosphere (processes and quantities), their fate (transport and chemistry), and their impact on the Earth system and ultimately on the present and the future health of the biosphere (including people). To that end, both for the quantification of greenhouse gases (GHG) and pollutants, complex EO systems combining satellite-borne, airborne, and ground-based instrument networks, together with models and data analytics, have been and are being developed nationally and globally. EO data of the atmosphere’s composition obtained remotely from the satellite infrastructure are inherently global. However, the quality of the satellite data sets is dependent upon a network of ground-based instruments for validation, which are overwhelmingly located in the northern hemisphere, and operated by the most industrialized countries. For example, there is no such validation site anywhere in Africa as far as GHG data are concerned. This introduces some significant geographical biases, associated to the local specificity of the land (albedo) and gas transport, affecting the global dataset quality and therefore its use for accurate monitoring and understanding of GHG- and AQ-related atmospheric processes. This is particularly detrimental to the global effort to transparently reduce GHG emission and improve AQ. The aim of the project is to establish a UK/South Africa long term collaboration towards augmenting the global EO ground-based capabilities, essential to maintaining and validating the accuracy of GHG and AQ measurements made remotely from satellites and to relate local measurements to global datasets. By leveraging the expertise of STFC RAL Space and NRF South African Environmental Observation Network, the primary objective is to establish a first validation site in South Africa with ground-based remote sensing instrumentation relevant to GHG and AQ, collect a dataset over a season, analyse the data using advanced algorithms, and demonstrate their added value to the EO and atmospheric composition sciences. In addition, a novel, machine-learning approach to use satellite observations to extend surface network measurements of pollutants across South Africa will be demonstrated. Through this seminal project, the project team intends to produce evidence in support of the establishment of a permanent ground-based reference EO validation site in an under-sampled region of the world; ultimately to be integrated into the international satellite validation networks and to contribute to addressing global environmental issues. Such an ‘EO super-site’ is ideal for capacity building, strengthening UK/South Africa collaborative links, improving both infrastructure and skills, training the next generation of EO scientists and technologists, and growing knowledge and understanding in atmospheric composition, with a relation to land GHG emission and AQ that can inform policy and possible actions.
Potential of sub-seasonal Operational Weather and climate information for building Energy Resilience in Kenya (POWER-Kenya)
DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY
Context and Challenges Kenya Vision 2030 identifies energy as a key infrastructural enabler for social and economic development, aiming for universal energy access and 100% renewable energy by 2030. Currently, 54% of Kenyans, and up to 84% in rural areas, lack access to sustainable modern energy, relying on traditional wood fuels for cooking and heating. Kenya's energy generation is particularly sensitive to weather variability, with nearly 50% of electricity coming from weather-sensitive sources like hydro, wind, and solar power. Achieving the ambitious goal of 100% renewables requires doubling the current capacity of these weather-sensitive sources. Despite the growing reliance on renewable energy, Kenya lacks reliable weather and climate information for effective energy planning, particularly on sub-seasonal timescales (weeks to months in advance). This gap impacts crucial decisions such as generator maintenance scheduling, international market trading, water conservation, and future energy storage management. In comparison, other regions like Europe have more advanced user-relevant tools for renewable energy decision-making. Aims and Objectives POWER-Kenya seeks to bridge the gap between Kenya's increasing dependence on weather-sensitive renewable energy and the lack of reliable weather and climate information to support energy planning. The project also aims to build capacity for integrated climate-energy research in Kenya. Its objectives are: Ob1: Deliver a step-change in the underpinning physical science to support affordable, clean energy by advancing understanding of sub-seasonal predictability of weather-sensitive demand and renewables. Ob2: Build combined climate-energy research capacity to continue improvements in maintaining reliable energy supply in Africa, facilitating the creation of risk-informed tools for energy decision-making to benefit both society and the economy. Acknowledging Kenya’s continent-leading capabilities in climate and energy fields individually, the POWER-Kenya project brings together UK and African expertise in electricity demand and renewable energy modelling (Bloomfield, Oludhe, Brayshaw, Olago), with the forefront of research on sub-seasonal predictability (Hirons, Gitau, Woolnough), and expert knowledge of East African climate (Wainwright, Mutemi, Hirons) to conduct world-leading energy-climate research to support this step-change in understanding (Ob1) and build partnerships and capacity (Ob2) capable of supporting Kenya’s climate-smart shift to reliable renewables. Applications and Benefits. Universal access to affordable, clean energy helps emerging economies like Kenya progress towards their Sustainable Development Goals by building businesses and societies capable of producing and consuming sustainably for a climate-resilient future. However, access to reliable energy has societal benefits far beyond sustainable economic growth. Reliable energy access can empower women, and other marginalised groups, by improving access to services such as mobile technology, online banking, educational materials, and employment opportunities. Access to clean energy, especially for currently unconnected rural households, can enhance health outcomes by reducing reliance on traditional wood fuels, which are linked to respiratory diseases. Achieving POWER-Kenya aims to ensure Kenya's shift to clean, weather-sensitive renewables is backed by current scientific thinking and proven techniques that will help deliver the country's aim for reliable energy for all businesses and households. Beyond Kenya, POWER-Kenya outcomes will inform and support the aims of the wider Eastern Africa Power Pool (EAPP) - an institution that coordinates regional cross-border power trade and grid interconnection. KenGen, a key project partner and regional leader, is a utilities member of the EAPP. Through iterative dialogue with POWER-Kenya, KenGen will help co-design the research, by defining energy stress case studies, and ensure it remains solutions-orientated and maximises benefits for Kenya and the broader region.
Sharing the sky – Using a global robotic telescope network for capacity and research community building in East Africa
DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY
We will provide a skills development programme for the astronomy communities in Kenya, Tanzania, Uganda, and Rwanda through observational projects with the Las Cumbres Observatory (LCO) 1m global telescope network. Acknowledging the specific value of fundamental sciences for long-term sustainable economic development, we address the prevalent barrier of lack of access to world-leading research facilities. Moreover, experience has shown that facility access needs to be paired with active engagement with potential user communities and a gradual development of expertise and experience in order to eventually develop strong research programmes. Our programme involves four national coordinators in each respective country who will act as focal point for their local community. Rather than building a single research project that focuses on a small number of individuals, we aim at supporting and growing whole communities at large, not only covering researchers with a PhD, but also PhD students and undergraduate research projects. Dedicated in-person workshops, covering observational and statistical techniques as well as campaign design and management, will accompany the target community along their research journey with the LCO network and support building inter-African collaborations, as well as path towards independence and African leadership (not being reliant on the strength of a non-African partner) as part of an integrated process. The opportunity for less resourced countries is in innovation, building on the creativity of its people to eventually shape new global trends. This provides potential to leap ahead rather than just trying to catch up. We will therefore particularly support research projects that trial new ideas or approaches, while providing pathways to larger projects and internationally competitive facility proposals. LCO uniquely combines the features of fast response, uninterrupted long-term monitoring, and full-sky coverage, resulting from a purpose-built design for observing astronomical transient events with durations ranging from seconds to several years. We will be getting astronomy research communities in East Africa ready for the unprecedented flood of alerts on transients of up to 10,000,000 per night from the LSST survey, expected from early 2026.
Bridging the Efficiency Gap of Metal vs Carbon back Electrode Perovskite Solar Cells to Support the Clean Energy Growth Transition in South Africa
DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY
Affordable energy for all Africans is the immediate and absolute priority in the Sustainable Africa Scenario (SAS) 2030. According to the International Energy Agency (IEA) Africa Energy Outlook 2022 report, solar energy-based mini-grids and stand-alone systems are the most viable solutions to electrify rural areas, where over 80% of the electricity-deprived people live [1]. Though Africa has 60% of the best solar resources globally, it has only 1% of installed solar photovoltaic (PV) capacity. Thus more investment and effective solar PV capacity building is required in the region to make electricity from clean energy sources as the backbone of Africa’s new energy systems. The existing silicon PV technology alone cannot meet this demand as it is an expensive mature technology, with global materials security issues, and enormous quantities of PV waste with poor recycling options [2]. Emerging PV technologies such as halide perovskite solar cells combine the unique properties of high power conversion efficiency (>25 %), low-cost printability, and provision to adopt a circular economy to ensure a sustainable clean energy transition for the region [3,4]. Halide perovskite PV offers the lowest cost of solar PV to date (<32 $ per MW h) and it matches with the levelised cost of electricity by solar PV (18-49 $ per MWh) required in Africa in the Sustainable Africa Scenario, 2020-2030. However, the mainstream highly efficient halide perovskite solar cells (PSCs) use thermally evaporated metals such as gold (Au), silver (Ag), copper (Cu) etc as the back electrode. These metals account for 98 % of the cost, 65 % of the carbon footprint and 45 % of the energetic cost of perovskite solar cells [5]. Replacing these metal electrodes with carbon electrodes enhances the stability, scalability and commercialisation aspect of PSCs along with further reduction in cost and carbon footprint. However, carbon back electrode-based PSCs (c-PSCs) have consistently lower power conversion efficiency (PCE) compared to metal electrode-based PSCs (m-PSCs) (20 % vs 26 % efficiency comparison for 0.1 cm2 area devices) limiting their commercialisation. The proposed project aims to bridge the gap in power conversion efficiency between the carbon-back vs metal electrode-based PSCs and demonstrate low-cost and highly efficient (>15 %) printable carbon electrode-based mini modules (10 x 10 cm2). This aim will be realised by combining the strengths of know-how in the fabrication and device physics of efficient halide perovskite solar cells of UK-based physicists with the defect analysis strengths of African physicists. To bridge this efficiency gap, the challenges to overcome are (i) reducing the interfacial losses and (ii) efficient photon management inside the perovskite active layer and the research objectives are identified accordingly. The proposed aims and objectives will formulate the foundations for achieving the vision for the proposed project: to provide accelerated growth in the scale-up of cheaper and cleaner energy sources in South Africa to achieve Sustainable Africa Scenario 2030 through capacity building in cost-effective and efficient PSCs in the partnering institution (University of Pretoria) in South Africa. References: IEA Africa Energy Outlook 2022 Charles et al Energy Environ. Sci., 2023, 16, 3711 Carneiro et al Energy Reports 2022, 8, 475 Faini et al MRS BULLETIN 2024, 49 Zouhair Sol. RRL 2024, 8, 2300929
Building the foundation for geodetic excellence in Africa through the Africa-UK Physics Partnership
DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY
Geodesy measures the Earth’s time-variable size, shape, and gravity. Its role is fundamental to various scientific areas, such as navigation and mapping, climate change, engineering, meteorology, and natural hazards. The precise geographical information systems (GIS) produced by geodesy are essential for delivering services to people, households, and businesses, administering land rights and development permits, and developing and maintaining national and regional infrastructures to access water, waste management, electricity, transport, schooling, health facilities, markets, and security. As a result, geodesy has been noted to contribute directly and indirectly to all of the United Nations Sustainable Development Goals (SDGs). However, the status of geodetic infrastructure on the African continent needs to be fully documented, and the existing infrastructure must be made more extensive to enable African nations to participate in and contribute to global geodesy effectively. This project seeks to address these challenges by laying the groundwork for a comprehensive understanding and enhancement of the geodetic infrastructure in Africa. It will assess the current state of geodetic equipment, computational infrastructure, and human capacity across critical African nations, including South Africa, Tanzania, Ghana, Kenya, Rwanda, and Uganda. By conducting a detailed inventory and analyses of existing resources, the project will identify critical gaps and opportunities for enhancement and strategically plan for new infrastructure development. The project will tackle these challenges by using advanced simulation techniques to assess where new infrastructure would be most beneficial, ensuring that future investments are strategically targeted and cost-effective for maximal impact. This foundational work is essential for enabling Africa to build a robust and sustainable geodetic infrastructure that aligns with global standards and meets the continent's unique needs. One of the most significant benefits of this project is its potential to substantially enhance Africa’s contribution to global geodesy. By laying the groundwork for improved infrastructure and capacity, the project will enable African nations to play a more active role in international geodetic initiatives, such as those outlined in the UN General Assembly Resolution A/RES/69/266, "A Global Geodetic Reference Frame for Sustainable Development." This will benefit the scientific community and support policymakers in making informed decisions related to many areas, such as climate change, disaster management, and urban planning. In addition to its scientific and policy implications, the project will have broader societal benefits. By promoting awareness of the importance of geodesy and encouraging greater participation from underrepresented groups, particularly women, the project will contribute to a more inclusive and diverse geodetic community in Africa. Furthermore, the knowledge and skills gained through this project will have applications beyond geodesy, supporting advancements in environmental monitoring, agriculture, and infrastructure development. In summary, this project aims to establish a solid foundation for the future development of geodetic infrastructure in Africa, ensuring that the continent is well-positioned to meet its own needs while contributing to global geodetic science. The project will create the conditions necessary to establish GGOS Africa, an affiliate of the Global Geodetic Observing System (GGOS), through detailed infrastructure assessment, capacity building, and strategic planning. This regional body will coordinate geodetic activities and further integrate Africa into the global geodetic community.
Efficient Photoelectrochemical Green Energy System based on Hematite Photoanodes Heterostructured with Selected 2D Transitional Metal Dichalcogenides
DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY
This project addresses the urgent need for sustainable energy solutions by enhancing photoelectrochemical (PEC) water-splitting technologies, which convert solar energy into storable hydrogen fuel. With the increasing global focus on mitigating climate change, the development of efficient, renewable energy technologies is paramount. PEC water splitting, a process that uses sunlight to produce hydrogen, presents a promising pathway to this goal. Our initiative centres on improving the efficiency of hematite-based PEC devices through innovative heterostructures incorporating two-dimensional (2D) transition metal dichalcogenides (TMDCs), such as SnS₂, MoS₂, SnSe₂, and MoSe₂. Hematite has long been studied for its potential in solar-driven water splitting due to its strong visible light absorption and favourable theoretical solar-to-hydrogen (STH) conversion efficiency. However, its practical application has been limited by issues such as poor electrical conductivity, slow charge transport, and high recombination rates of electron-hole pairs. By integrating hematite with 2D TMDCs, we aim to overcome these challenges, enhancing the material’s performance through improved charge transfer, reduced recombination losses, and optimised band alignment. This approach promises to boost STH conversion efficiency and achieve the 10% benchmark set for practical applications, making a significant contribution to the development of scalable, clean energy solutions. The project not only advances scientific knowledge but also brings substantial benefits to researchers and institutions in Africa. The collaboration between UK and African institutions facilitates access to cutting-edge facilities and expertise in the UK, which are critical for the successful implementation of this research. African researchers will have the opportunity to train on advanced characterisation tools and gain hands-on experience with state-of-the-art PEC technologies. This exposure is invaluable for building their technical skills and enhancing their research capabilities. Moreover, the project fosters networking and collaborative opportunities between African and UK researchers, promoting the exchange of knowledge and ideas. This international collaboration helps to strengthen research networks, opening doors for future partnerships and joint ventures. African institutions will benefit from the establishment of sustainable partnerships and the development of local expertise in advanced energy technologies. Additionally, the project includes outreach and dissemination activities, which will raise awareness and engage various stakeholders, including the public and industry players. These activities will not only highlight the advancements in PEC technology but also showcase the contributions of African researchers to global scientific progress. In summary, this project is poised to make significant strides in improving PEC water-splitting efficiency, with the added advantage of enhancing research capacity and collaboration between African and UK institutions. By addressing key challenges in renewable energy technology and providing valuable training and networking opportunities, the project aims to contribute to the global transition to clean energy while strengthening the scientific community in Africa.
SAPPHIRE : Supra-African Physics Partnership for Health Innovation and Radiotherapy Expansion
DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY
Vision: SAPPHIRE is a UK-African research and training partnership which will build capacity in Africa to obtain better fault information of M-LINACs and to feed into an M-LINAC tailored to low- and middle-income countries (LMICs). Importance: Our previous STFC funded ITAR project surveyed 28 African countries, revealing two major challenges: 1) many African M-LINACs suffer from considerable down-time down due to frequent breakdowns of specific components; and 2) a shortfall exists in radiotherapy workforce, especially trained physicists. Team: We will bring together M-LINAC facilities in Accra and Kumasi (Ghana) and Pretoria (South Africa), two STFC accelerator centres in Oxford & Lancaster, and medical physics expertise from Cambridge in partnership with CERN and ICEC. Our global team has decades of experience in accelerator and M-LINAC research and has engaged in collaboration with African partners since 2010. Areas of Focus: Specific focus will be given to post-acceleration beam-shaping systems that match radiation beam to tumour target (i.e. multi-leaf collimator devices). MLCs are prone to frequent breakdowns. Project SAPPHIRE has 3 key objectives: Objective 1: To identify junior physicists in Africa to train in electronic data collection and analysis of usage and fault data from M-LINAC stock in their own centres. Objective 2: To use gathered data to assess the effect of faults and to define MLC tolerances, studying different candidate leaf designs for an improved and robust MLC unit. Objective 3: To compare the performance of candidate designs with current-generation commercial M-LINAC devices for treatment planning using real-world clinical data. We will achieve these objectives through four key Physics Education And Research Linkage work packages (PEARLs): PEARL-1 Data Capture. We will create a solution for electronic data capture (EDC) of M-LINAC fault and usage data, enhanced with key environmental factors (e.g. operating temperature, voltage stability, humidity and atmospheric particulate levels). Hasford, Addison and Nethwadzi will supervise training of junior physicists for EDC work in Ghana and South Africa. PEARL-2 MLC Improvements. Dosanjh, Burt, Addison, Hasford and Nethwadzi will develop an understanding of the causes of MLC faults, analyse the implications on the radiation patterns using Geant4 and develop improvements of the MLC design. This will allow researchers throughout our collaboration to investigate the relationship between reported fault and environmental data and the design constraints of the MLC. PEARL-3 Training workshops. Burt, Dosanjh, Jena, Ayette, Addison, Grover, Hasford, and Nethwadzi will establish two physics schools in Africa, first one in Ghana focussing on LINACs, their sub-components and faults/maintenance of those system and the second in Pretoria focussing on radiation physics simulations and imaging and treatment planning. PEARL-4 Treatment planning. Jena, Dosanjh, Ayette and Grover, will compare the performance of candidate hardware designs with current-generation commercial M-LINAC devices in a suite of treatment planning tasks typical of today’s clinical demands. Pathway to success: 1) We have a rich and capable multi-professional team and a long track record of successful collaboration. 2) We will make lasting impact through successful upskilling of junior physics staff in Africa, to perform better research and development in M-LINAC component design and operational robustness. 3) Data from SAPPHIRE will be used by our global consortium (ICEC) to design and deploy a novel fault tolerant M-LINAC design for LMICs by 2030.
Temperature-sensitive Earth-abundant Catalysts for green Hydrogen production
DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY
Hydrogen production via water electrolysis technology has been a major focus of discussions for practical carbon-neutral transportation fuel and a key component for other chemical syntheses for the past decade. Particularly, Africa’s total announced electrolyser pipeline capacity has reached 114 gigawatts. However, the costs of water electrolysis to be reported in the range of 2-5 £/kg H2, which is still twice as expensive as the existing fossil fuel-based technologies. Among various electrolyser technologies for hydrogen production, alkaline water electrolysis is considered to be the most mature type for industrial scale-up and has strong cost-effectiveness. Despite these advantages, its cold-start nature, unfortunately, requires a certain ramping-up time (approximately 1 hour). This makes it challenging to integrate with renewable energy sources, which are difficult to predict. Alkaline water electrolysis at elevated starting temperatures offers a promising solution to enhance catalytic reactivity and reduce required electric energy, increasing cost-effectiveness. The cobalt- and nickel-based catalysts, known for their prominent temperature dependence, could be the key to enhancing the hydrogen production rate. In this study, we aim to establish a feasible fabrication method of temperature-sensitive catalysts for alkaline water electrolysis and to explore the multi-element catalysts' physical and chemical bonding structure change at elevated temperature conditions. Exploring the underlying mechanism of intrinsic kinetics change is a challenging yet crucial step towards more efficient and cost-effective hydrogen production. The ultimate goal of the proposed collaboration entitled "Temperature-sensitive Earth-abundant Catalysts for green HYDROgen production (TECHydro)" is not to develop new catalysts but to discover new combinations that have a high-temperature sensitivity and explore underlying principles, giving rise to fresh perspectives of the developed catalyst for their application to AWE. The outcomes will provide a methodological achievement in cost-effective catalyst preparation. Moreover, the project will make a rigid bridge for further joint-research funding applications and staff exchange between African (South Africa and Kenya) and UK partners. We believe that the outcomes of this study could set benchmarks for hydrogen production that operates more efficiently in South Africa and Kenya's hot climate, contributing to the global transition towards a hydrogen economy.
Compound-Semiconductor-Enabled Renewable Energy System for Powering Critical Buildings in Africa
DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY
Africa’s power supply systems for critical loads, such as healthcare facilities, are transitioning to a more sustainable, efficient and reliable future. This is driven by the integration of renewable energy, which includes AC and DC power conversion enabled by power semiconductors switching at increasingly high frequencies (e.g., 10–100 kHz). The semiconductors’ operation causes power loss, reducing energy efficiency, and they are the most vulnerable components, counting for 20%–30% of the failure of power conversion systems. Improving the performance of the semiconductors will thus provide significant benefits in energy saving and system reliability improvement. For example, a 1% increase in efficiency in solar photovoltaic (PV) inverters and a 1% in reliability will make 150 GWh more energy available to critical healthcare facilities in Africa. This project’s overarching aim is to leverage the latest advancements in Silicon Carbon (SiC) semiconductor technology to develop high-efficiency and reliable solar photovoltaic-battery energy storage system (PV-BESS) for critical loads. Such compound semiconductors have low conduction loss, fast switching speed, and high operating temperature, which provides all potential for developing low-carbon PV-BESS. Challenges are that high-frequency switching of SiC semiconductors can increase thermal stress and create electromagnetic interference (EMI) due to their high-speed voltage transients (e.g. dv/dt over 10kV/us), affecting the reliability of the PV-BESS and lifespan of critical components such as capacitors and batteries. SiC semiconductors exhibit various material defects and variability, leading to variations and high non-linearities in their electro-thermal performances. Integrating SiC semiconductors into PV-BESS requires a better understanding of induced parasitic parameters and their coupling with components, including capacitors, inductances and gate drivers. To address these issues, the project has three research work packages (WP1-3): Develop accurate characterisation and modelling methods for semiconductor devices (WP1): Accurate SiC electro-thermal models and lifetime models will provide a new understanding of SiC semiconductors, which will be built to evaluate component efficiency and reliability under various environments. Integration optimisation of SiC-based PV-BESS (WP2): This involves studying and modelling the multiphysics coupling between SiC semiconductors and other components, investigation of induced parasitic parameters and system-level topology design of PV-BESS to reduce power conversion stages, thus improving overall efficiency and reliability. Validation and operation optimisation of SiC-based BESS in various operation conditions (WP3): This will investigate integration strategies and verify the benefits brought by SiC devices' advantages to ensuring the BESS’s high-efficiency and reliable operation in both normal and fault conditions. The main deliverables will include validated tools and a testbed for modelling and characterisation of SiC semiconductors (WP1), hardware-in-the-loop demonstrator for validating the SiC-based PV-BESS (WP2), and optimal operation strategies for PV-BESS (WP3). These will be useful to physics R&D institutions, renewable equipment vendors, and power system operators. The project will involve international partnerships with the University of Nairobi, with support from Scottish Power Energy Networks (SPEN) and Toshiba Europe. Researchers involved will benefit from the unique collaboration and training, and the project will help Africa build new physics research capacities in the renewable energy and semiconductor sectors. The project output will boost the PV-BESS’ energy conversion efficiency by 1%–2%, and extend their mean-time-between-failures by 20%. Developed compound semiconductor technologies will have a wider impact across applied industries, including electrified transportation sectors, robotics and aerospace. The integration and BESS technologies can be extended to generic low—and medium-voltage energy systems.
Frugal Innovation for Societally-Important Challenges in Africa (FISICA)
DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY
Historically, Physics is seen to be a key driver of novel techniques and instrumentation that draw on our advances in scientific understanding. Such instrumentation often plays a critical role in helping to solve societal challenges in areas such as agriculture, climate change, energy generation, and healthcare. Sadly, much state-of-the-art technology is prohibitively expensive for developing countries, limiting its adoption. Here, we will bring together partners from the UK and several African countries – Ghana, Rwanda, South Africa and Tanzania – to collaborate on developing cost-effective instrumentation. The two types of instrumentation to be worked on are a hyperspectral imager and a gamma-ray spectrometer: A hyperspectral imager is an instrument that can be used to analyse fine details of the light reflected by the leaves of plants in different parts of the visible or infra-red spectrum. The properties of this reflected light turn out to be very sensitive to the health of plants or crops. In this manner, a hyperspectral imager can be a major benefit to monitoring of crops and other aspects of agricultural development. A gamma-ray spectrometer is an instrument that is sensitive to gamma radiation. Gamma radiation is emitted from so-called naturally occurring radioactive material (NORM) found in certain rocks, minerals and soils. A gamma-ray spectrometer can both quantify the radiation and identify its origin. This project will begin with two workshops: one in the UK and one in South Africa. The workshops will be facilitated by experts in innovation to help the project partners co-create mini projects making use of the novel instrumentation to address challenges specific to their own localities, with a particular focus on issues such as agriculture and climate change. The project will deliberately challenge people to work in a highly interdisciplinary way and collaborate with other researchers well outside their immediate field of expertise. Impacts are expected not only in technology development but also from the field trials to be carried out with the novel instruments. The project will also lead to capability building and upskilling of significant numbers of early career researchers at universities and organisations across several Africa countries. The project builds on existing strong collaborations between the University of York in the UK and three Universities in South Africa: University of Pretoria (UP), University of the Western Cape (UWC) and the University of Zululand (UZ). Indeed, this new project will, in part, exploit earlier STFC investments (Funder Award Reference ST/S003118/1) that built the Modern African Nuclear DEtector LAboratory (MANDELA) at the two historically disadvantaged universities, UWC and UZ.
Stability of the South African Power Grid ---A data-driven Statistical Physics-based Approach
DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY
South Africa (SA) primarily relies on coal-fired power plants for its electricity supply. At least 12% of the population does not have access to power and roughly 10% cannot adequately afford electricity, particularly in rural areas. There is a particular challenge with reliable electricity supply in SA, as currently there is inability to deliver sufficient power according to the country’s demand. This has led to the implementation of rolling blackout load shedding events across the country. Load shedding has marked deleterious societal effects. In 2021, the citizens and industries of SA were afflicted by a lack of power and periodic load shedding for over 48 days of the year. There are also unplanned outages (known as non-technical losses) for parts of the network. During electricity outages, people and households typically use Diesel generators (if they can afford them), others simply remain without power. The use of Diesel generators during load shedding periods has severe detrimental effects, in financial, environmental, and health terms. Diesel generators are also frequently used in other African countries if there is no reliable connection to the power grid. Our project aims to better understand, model, and mitigate the above load shedding situations in SA, working towards sustainable solutions (alternatives to Diesel generators) with no Carbon emissions that can be afforded by all. The overall aim is to model, understand and improve the stability of the African power grid using methods from statistical physics. To model the South African power grid as a whole, we will be using cutting-edge research methods in statistical physics modelling of complex systems, data-driven analysis and machine learning. A central aspect of our work plan will be the analysis of frequency fluctuations in the main grid, the control of microgrids, and the analysis of wind energy statistics, working towards future implementation of zero-emission generators based on wind power, solar panels, and batteries. We will model and analyse the overall demand patterns of electricity consumers in SA in a data-driven way, to finally arrive at practical solutions and concrete mitigation strategies. We aim at solutions that are particularly suited for the poorest in SA. At the same time our approach will contribute to lowering the Carbon footprint of SA in the long-term. The main general objectives of our proposal are as follows: Model and forecast the stability of the SA power grid. Model the fluctuating electricity demand of individual households in a data-driven statistical-physics inspired way. From a complex system point of view, take up the challenge of modelling a system where demand and supply don’t match. Model microgrids that use Diesel generators and/or zero-emission generators during load shedding periods. Measure frequency fluctuations in the grid and feed the data into theoretical statistical-physics based models. Develop statistical physics models that capture the essential features of the dynamics. Using neural nets, predict wind power fluctuations in SA. Prepare the ground for long-term mitigation strategies and a reliable electricity supply for all (in particular the poorest communities in SA) during load shedding periods and beyond, based on wind power, photovoltaic systems, and batteries. Foster new scientific collaborations between SA and the UK, dealing with statistical physics-based modelling of power grids. Work together towards a long-term strategy where power is provided in a reliable way, at the same time reducing the Carbon footprint of SA.
IKIRERE - Innovation And Knowledge Integration For Resilience In East Africa Through Climate Research And Education
DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY
Climate extremes such as droughts, floods and heatwaves affect many parts of the world, already having devastating impacts on human health, food security, livelihoods, infrastructure and water resources. East Africa is one of the regions most prone to these extreme events, and particularly vulnerable due to its strong reliance on rain-fed agriculture and limited resources to mitigate their effects. As climate change intensifies, these extreme events are predicted to be longer, more severe and more frequent, thus adding extra pressure on already overburdened developing nations, who have contributed the least to the greenhouse gas emissions causing global warming. One way to help East African nations adapt to climate change and be more resilient to extreme events is through improved understanding of the drivers and indicators of these phenomena, which can be used to develop effective early-warning systems. However, there are still a lot of uncertainties around how these extreme events develop in the region and what early indications may exist. Some of the barriers these countries face are a lack of measurements on the ground, limited access to data, and reduced capacity to undertake the necessary research due to lack of funding and low uptake of physics as a career (including climate physics), particularly by women. In this project (‘IKIRERE’, which means ‘climate’ in Kinyarwanda) we have partnered with colleagues in Rwanda and Tanzania to address two key climate change challenges affecting their societies and economies: uncertainties related to drought and heatwaves, and the reduced capacity in the field of climate physics. By combining scientific and capacity-building activities we will provide a comprehensive solution that not only sheds light on two pressing issues, namely droughts and heatwaves, but also contributes to building the next generation of local talent that will help their countries independently research, manage, mitigate and adapt to climate challenges in the long term. Our objectives are: Generate new knowledge of soil moisture droughts and heatwaves in East Africa through the use of physical process models, state-of-the-art methods and datasets. Exploit new technological methods, including explainable AI and physics-based machine-learning emulators. Build the capacity of early-career African researchers through dedicated workshops, with a focus on gender equality. Raise awareness of the importance of quality physics-based climate research through outreach in schools, including resources for primary schools and a dedicated Physics-Camp workshop for older pupils. We expect the outcomes of this project will have many benefits and applications. Some of the methods and tools developed for IKIRERE will be the building blocks for a future Digital Twin of droughts and heatwaves, which will help democratise access to climate data and provide decision support to stakeholders. The new knowledge of droughts and heatwaves will form the basis of new early-warning systems and help inform the affected countries to be better prepared for future events. The new educational tools and materials, supported by the UK STEM Learning Centre and GEO/CEOS, will reach large numbers of users through our collaboration with Digital Earth Africa. The school activities and dedicated physics workshops will train and inspire a wide range of local students and researchers, who may go on to take careers in climate physics. Finally, the dedicated gender equality workshop will raise awareness of the unique issues women face to the uptake of STEM careers and help break barriers.
Simulation-based inference for the Square Kilometre Array and Beyond
DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY
The Square Kilometre Array (SKA) is an international project with worldwide participation, to analyse radio signals from the Universe with two very large footprint telescope arrays across 9 African countries and Australia. The SKA will arguably be the largest fundamental science project ever undertaken and will open a new window on the Universe, shedding light on key unsolved problems in astronomy and cosmology. The huge volumes and sensitivity of the data from the SKA present a number of key challenges. One of the most pressing is the contaminating noise from radio-frequency interference (RFI) from the ever-growing number of cell phones, satellites, radio stations and television broadcasts. Efficiently dealing with this RFI at the multi-petabyte scale of the SKA requires rigorous new statistical and computation methods that bridge traditional statistics and cutting-edge machine learning and Artificial Intelligence. It represents a unique opportunity to build scientific capacity in Africa. The proposal is designed to contribute to this, through two main elements: the specialised training of two early-career SKA researchers, one in South Africa and one at Imperial College, focussed on recruiting from Africa; and the broader impact of training around 30-40 students from across Africa at the interface of statistics and artificial intelligence through a dedicated summer school and workshop. We aim to provide this training free to the students. The specialised research project has four main components: simulation, emulation, data compression, and statistical inference. Although this targets the SKA, the skills are broadly applicable to many areas where inference with complex simulations are important, including climate modelling, epidemiology and manufacturing. The proposers are leaders in all of the core method areas and have extensive experience in the training of junior researchers, and are ideally placed to impart this knowledge. In addition, the proposers have a proven track record of working effectively together.
Development and assessment of novel, high-throughput immunological assays to improve surveillance of spillover of viral families of pandemic potential
DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY
Context Emerging infections pose a significant burden on healthcare systems and result in economic loss for societies worldwide as exemplified by the COVID-19 pandemic. Another new viral pathogen, causing ‘disease X’, will likely emerge in the future and pandemic preparedness is thus one of the top priorities of global agencies (UN, WHO, G20) and national governments. Vulnerable health systems, dense populations with close human-animal interactions, rapid urbanization and economic development, and stark health inequalities render Southeast Asia a hotspot for outbreaks of new and existing infectious pathogens, in particular zoonotic viruses. Yet, the region represents a weakness in pandemic preparedness and response. The challenge the project addresses Early detection of spillover events is critical to informing coordinated global responses, including the rapid development and deployment of effective and safe countermeasures, (especially diagnostics, therapeutics and vaccines) to prevent future pandemics or mitigate their health and societal impact. Existing surveillance platforms are primarily based on clinical diagnosis in healthcare settings supplemented, in some areas, by genomic surveillance. They often therefore fail to capture early cases and those with asymptomatic or mild infection. Despite their potential utility, owing to the current low throughput and technical challenges, antibody and T-cell assays are rarely used for zoonotic spillover detection. Here, we will first develop high-throughput, high-resolution antibody and T-cell assays to enable early detection of spillover events. We will then apply the developed assays to comprehensively map out the immune landscape against zoonotic viruses of the families Coronaviridae, Orthomyxoviridae and Paramyxoviridae in high-risk populations in Cambodia and Vietnam. The data will be used to evaluate how immunological data could be utilised as part of broader surveillance strategies and estimate their potential to improve earlier detection of spillover events. Finally, potent, broadly neutralizing antibodies against zoonotic viruses will be discovered using samples collected from study participants with a confirmed infection. Aims and objectives Our aims are To develop novel, high-throughput immunological tools for viral families of epidemic/pandemic potential To apply the assays developed under Aim 1 to map out the immune landscape against zoonotic viruses with pandemic potential in high-risk populations in Cambodia and Vietnam To utilize the data from Aims 1 and 2 to evaluate the utility of the novel immunological tools as part of broader surveillance strategies and estimate their potential to improve earlier detection of spillover events To discover potent and broadly neutralising antibodies against zoonotic viruses causing spillover documented under Aim 2 Potential applications and benefits Our project will ultimately build regional research capacity in immunology, metagenomics, modeling and monoclonal antibody discovery in Cambodia and Vietnam. Importantly, a strong collaborative network across the region, linked with international experts in the UK and Singapore will be established. Therefore, our collective outputs would lay the foundation for locally-led responses to future emerging infections.
Studying Hygiene Interventions to reduce Nosocomial Infections in southeast Asian Intensive Care Units (SHINIA-ICU )
DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY
It has recently been estimated that 1.7 million AMR-associated deaths in low-income and middle-income countries (LMICs) are due to health-care associated infections. A substantial proportion of these deaths could be prevented through improving infection prevention and control programmes through low-cost multimodal interventions, but achieving these reductions requires overcoming chronic under-investment in such interventions in LMICs. Such underinvestment stems from the limited evidence base regarding the effectiveness and cost-effectiveness of such multimodal interventions in LMIC settings, lack of knowledge about the potential health gains achievable, and uncertainty about the best way to spend limited budgets to achieve these gains. Our proposal aims to address these evidence gaps by generating robust and generalisable evidence about multimodal hygiene interventions in hospitals in LMICs in southeast Asia and to equip regional decision-makers with the knowledge and tools needed to enable appropriate investments in hospital infection prevention and control programmes. The role of hospital environment-mediated pathogen transmission is well-recognized in healthcare-associated infections, which are often caused by micro-organisms which are resistant to multiple drugs. Contaminated surfaces harbouring these pathogens sustain the spread of drug-resistant bacterial clones and mobile genetic elements (which can spread drug-resistance between bacterial species) in outbreak and non-outbreak settings. Despite an emphasis on environmental hygiene and the availability of international guidelines, there is insufficient evidence in the current literature to identify the most effective (and cost-effective) setting-specific cleaning strategies to reduce transmission of multidrug-resistant organisms, especially in LMICs. This contributes to the low awareness and prioritisation of environmental cleaning in these resource-limited settings and potentially to underutilisation of low cost and high impact interventions. Our prior work has highlighted the fundamental role of hospital environment hygiene in breaking the vicious cycle of antimicrobial overuse and the resultant high burden of multidrug-resistant healthcare-associated infections. Firstly, the epidemiology of healthcare-associated infections in the LMIC setting has shown an overwhelming predominance of environmental organisms such as Acinetobacter spp. and Pseudomonas spp. Secondly, lack of trust in infection prevention and control policies and rapid colonization by multidrug-resistant organisms amongst newly admitted patients are important drivers of broad-spectrum antibiotic prescriptions, especially in 'high-stake' wards such as intensive care units (ICUs). Thirdly, multimodal cleaning strategies have been shown to substantially reduce multidrug-resistant infections in high income countries, most prominently demonstrated in the REACH and CLEEN trials in Australia, with the latter reducing the chance of ICU patients acquiring infections from 17% to 12%. Aims and objectives The overall aim is to determine setting-appropriate and cost-effective interventions for improving environmental cleaning in low-resource settings, with a goal of reducing multidrug-resistant hospital-acquired infections and health-economic burden. Primary objective: Evaluate the effectiveness of locally optimized multimodal cleaning bundles to reduce multidrug-resistant hospital-acquired bloodstream infections and ventilator-associated pneumonia in ICUs. Secondary objectives: Evaluate the effectiveness of the cleaning bundles to reduce patient colonization by multidrug-resistant organisms in ICUs; Identify multidrug-resistant organism reservoirs and their respective ecological niches in the ICU environment; Assess thoroughness of cleaning for high-touch points; Model the transmission dynamics of multidrug-resistant organisms taking into account human and environmental hidden reservoirs; and, Evaluate the cost-effectiveness of cleaning bundles for preventing hospital-acquired bloodstream infections and ventilator-associated pneumonia 6. Develop an qualitative and quantitative understanding of the causal pathways between the intervention and any resulting changes in drug-resistant infections
Improving the detection of emerging zoonotic pathogens in forest fringe populations: can we achieve high quality spatio-temporal sampling?
DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY
Context: Many emerging infections (such as COVID-19, HIV), have arisen where people live in close proximity to wildlife. When a new infection crosses over from the wildlife to humans (zoonotic infections/pathogens), it usually takes time to establish, circulating in remote populations before entering urban environments. Fevers are a starting point for recognising an emerging infection. The development of new pathogen variants, which may make people sicker, often bring it to the attention of health care workers. Indigenous communities living in and around forest-fringes, such as those found in Indonesia, Malaysia, and many parts of Southeast Asia, are particularly vulnerable to emerging infections: these populations live near wildlife and their daily activities (such as farming/hunting) bring them into close contact with them. Insect-vectors also facilitate the spread of vector-borne diseases. These populations often have limited access to healthcare and can delay seeking care when unwell. Even when they seek care, diagnostic tests are limited. Further, fevers are commonly reported, but the causes of fevers are often not identified. Challenge: The recent COVID-19 pandemic is a stark reminder of the human and economic consequences of newly emerging infections. To prevent future epidemics/pandemics and their devastating consequences, we must engage with communities most-at-risk of emerging infections and develop context-specific, acceptable, feasible ways to rapidly identify emerging infections with epidemic/pandemic potential as they arise. This would facilitate early, rapid clinical and public health action at source. But how to do this is unclear. Given the high-risk of zoonotic infections, burden of reported fevers, and limited access to healthcare, innovative ways to diagnose fevers as they arise in high-risk indigenous forest-fringe communities are warranted. A community-led model of sample collection and testing to detect the like cause, may be appropriate. Combining this with newer genetic (DNA/RNA) techniques such as sequencing for detecting pathogens, may help us identify known and unknown pathogens. But we do not know if a community-led approach is feasible, acceptable, and achieves high coverage among indigenous forest-fringe populations and would give enough genetic material from samples for testing. Vector-borne diseases (e.g. malaria, dengue), transmitted by mosquitoes, are also common in these settings. Therefore, trapping and testing vectors for pathogens, may complement testing in humans. But how best to trap vectors in and around forest areas is not known. Aims and objectives: Therefore, we propose to co-develop a decentralised community-led community-sampling intervention package for fevers in two indigenous forest-fringe communities in Indonesia and Malaysia. Rapid diagnostic tests will be used for diagnosis with linkage-to-care for managing people with fevers. Acceptable sample-types will be collected, processed, and stored for sequencing. Using implementation research, we will determine if this approach is feasible, acceptable, and achieves high-coverage. We will also determine if this provides high-quantities of high-quality DNA/RNA required for sequencing, compared to collecting samples at healthcare facilities by trained research staff. Finally, we will evaluate different mosquito traps to identify the optimum trap for use in these communities. Benefits: Through this work, we aim to identify the ways to deliver services to detect emerging infections to indigenous forest-fringe communities across similar geographies. Our work, combined with the rapidly developing accessible sequencing technologies (and analysis methods), could inform on how to detect pathogens in a meaningful, sustainable way in high-risk, hard-to-reach populations.
Identifying drivers for the emergence and transmission of key human pathogens and AMR in Vietnam and the Philippines (AMR-VP)
DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY
Southeast Asia (SEA) remains particularly vulnerable to new and emerging disease threats due to poor infection control, unregulated antibiotic use, inadequate water sanitation, high population density and rapid urbanization. Sequencing technologies have transformed our understanding of infectious diseases and pathogen evolution, including the transmission of antimicrobial resistance (AMR). The COVID-19 pandemic highlighted the importance of frontier science efforts to analyse microbe diversity and its potential impacts on human health including the value of genomics-based approaches in tracking and tracing not only the presence of the virus but also its movement, enabling identification of where (and often how) new strains emerged. This enables resources to be targeted to ‘hotspots’ of emergence and ‘nodes’ of spread. It is of paramount importance that the knowledge and experience built during the pandemic are now consolidated and built on for other microbes with epidemic potential across One Health (OH) dimensions, i.e. in the food chain – in particular, multi-drug resistant bacteria, such as Acinetobacter baumannii, Klebsiella pneumonia, Escherichia coli, Salmonella spp. and Helicobacter pylori that have been prioritised in Vietnam and Philippines due to their ability to rapidly spread within environmental and human-animal interface or develop resistance to multiple antibiotics. Translating OH research priorities into action for human health is essential for the creation of evidence-based policies and programs for the prevention and control of infectious diseases and other health threats, and thus is an important component of a robust national capacity to effectively prevent, control, and mitigate biological incidents. Following, one of the most pivotal technical domains within an OH framework is understanding the emergence and evolution of key pathogens and AMR and one of the most pivotal research priorities that need to be translated into action for human health is limitations on inference regarding directionality of transmission or risk pathways deduced from conventional data. AMR-VP project brings together SEA and UK researchers working on interdisciplinary AMR challenges to study the epidemic potential of key human gastrointestinal pathogens and the molecular mechanisms underlying AMR in urban environmental, animal, food and human interface across major metropolitan areas in SEA, focusing on Manila (Philippines) and Ho Chi Minh City (Vietnam). Our project will adopt a systems approach to trace the origins and drivers of AMR bacteria overlapping with health practices, genetics, applied sciences, and social contexts. As the project progresses, pathogen and AMR dynamics will be analysed, comparing data across different contexts such as food systems and human activities to achieve its overarching objectives to: [1] provide training and capacity build for SEA researchers in next-generation sequencing (NGS) and bioinformatics, addressing identified weaknesses whilst simultaneously demonstrating the value of an OH systems approach, crucial for identifying epidemic strains circulating between humans, animals, and the environment in SEA; [2] explore the emergence, evolution and transmission of AMR and key resistant pathogens (A. baumannii, K. pneumonia, E. coli, Salmonella spp. and H. pylori) in and between human, animal and the environmental microbiomes within OH context; [3] perform big data analysis and systems modelling to identify transmission routes of these pathogens; and [4] develop artificial intelligence (AI) algorithms, based on machine learning, to expedite the genomic and epidemiological metadata in predicting epidemics, outbreaks and AMR. This will counteract the emergence, transmission and spread of bacterial pathogens and AMR, enhance genomic surveillance, improve targeted interventions, and boost public health resilience.
Academy of Medical Sciences - Global Policy Workshops - International Science Partnerships Fund
DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY
In accordance with the The Integrated Review of Security, Defence, Development and Foreign Policy, this scheme will seek to provide the UK with a strategic advantage, as it's intended that the networks/collaborations formed will be long-lasting, and will expedite the delivery of important research. The ODA funding, in particular, will facilitate the development of global science capability. However, it's hoped that all awards will contribute to tackling the global challenges, and within the scheme, there is a good chance of all priority themes being addressed. Opportunites such as this, which facilitate mobility, are powerful in terms of enhancing the UK's reputation, and contribute to the ambition for the UK to be a scientific superpower. The scheme has two funding streams: one for a selection of countries on the Development Assistance Committee (DAC) list of Official Development Assistance (ODA) recipients, to include the Least Developed Countries. The grants will help to: Deliver important science that can only be fully realised by working internationally; tackle global challenges and develop future technologies; positioning UK researchers and innovators at the heart of global solutions; and strengthen the influence and connections of the UK Research and Development (R&D) community domestically and around the world. The awards would provide up to £25,000 over one year to support collaborations between priority ODA countries and/or Least Developed Countries (LDCs) and the UK and to hold networking events aimed at addressing the priority themes identified for International Science Partnerships Fund (ISPF). The scheme would be a vehicle for researchers from across the disciplines to forge new links and generate innovative transdisciplinary research ideas. It's envisaged that these new networks will then be better positioned to compete for more substantive grants offered by future funding initiatives. This programme will be working with the British Academy, the Royal Academy of Engineering and the Royal Society to offer Networking Grants funded through the International Science Partnerships Fund (ISPF). This will allow UK-based researchers and innovators to collaborate with international partners on multidisciplinary projects. Furthermore, it will help the UK and its partners to deliver bigger, better science than one country can do alone.
Academy of Medical Sciences - Networking Awards
DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY
The awards would provide up to £25,000 over one year to support collaborations between priority ODA countries and/or LDCs and the UK and to hold networking events aimed at addressing the priority themes identified for ISPF. The scheme would be a vehicle for researchers from across the disciplines to forge new links and generate innovative transdisciplinary research ideas. It's envisaged that these new networks will then be better positioned to compete for more substantive grants offered by future funding initiatives.
Academy of Medical Sciences - International Career Development Programme -International Science Partnerships Fund
DEPARTMENT FOR SCIENCE, INNOVATION AND TECHNOLOGY
This programme builds on the Academy's extensive experience of developing programmes to support UK researchers through mentoring, tailored training in leadership, entrepreneurship and research soft skills and cohort-building Drawing on our experience of the ODA capacity building workshops piloted in 2022 and on recommendations that will emerge from the clinical research capacity building project, the career development programme will focus on identifying and fostering global best practice in supporting and connecting emerging research leaders across the health sciences sector (clinical, non-clinical, industry). Topics discussed and resources will be developed around wider leadership and entrepreneurship training, building supportive cohorts and in the second year connecting our UK cohorts with international emerging leaders for to exchange knowledge, foster collaborations and extend networks within life sciences. This activity potentially stimulate additional research impact by supporting researchers to thrive in their careers through opportunities for training, mentorship and cohort building, and also influence practice in terms of developing ways to support research careers and sharing best practice between UK and other countries. In addition, strengthen research capacity in developing countries by raising awareness and helping with the implementation of career support programmes that are important for researchers to thrive and be supported in carrying out their research, and working in partnership with organisations in partner countries, sharing best practice and forming connections between researchers in the UK and partner countries will strengthen the perceptions of UK research leadership and as a leader in the area of career development support. As with the global policy workshops, the ODA regional workshops will be developed and hosted in the ODA-eligible partner country and all outputs will be targeted towards the ODA-eligible partner country or region.
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