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Structured Operational Research and Training Initiative on building sustainable operational research capacity on antimicrobial resistance in LMICs

UK - Department of Health (DH)

The aim of this programme is to build sustainable operational research capacity to generate and utilize evidence on the emergence, spread and health impact of antimicrobial resistance (AMR), in order to limit this public health problem. The project uses the Structured Operational Research and Training Initiative (SORT IT) and targets a number of low- and middle-income countries, with special focus on Fleming Fund supported countries.

Programme identifier:

GB-GOV-10-AMR_SORT_IT

Start Date:

2018-11-20

Activity Status:

Implementation

Total Budget:

£8,212,943


Global Antibiotic Research and Development Partnership’s Neonatal Sepsis Programme (GARDP) support

UK - Department of Health (DH)

A partnership to fund the development of new treatments for severe bacterial infections in neonates under GARDP’s Neonatal Sepsis Programme

Programme identifier:

GB-GOV-10-PDP_GARDP_NS

Start Date:

2020-03-01

Activity Status:

Implementation

Total Budget:

£4,000,000


Research for Health in Humanitarian Crises (R2HC) phase III

UK - Department of Health (DH)

The UK Department of Health and Social Care (DHSC) funds outstanding global health research through the National Institute for Health Research (NIHR). The aim of the Research for Health in Humanitarian Crises (R2HC) programme is to develop more effective responses to humanitarian challenges by providing significant funding for high-quality research on the effectiveness of health interventions in humanitarian crises.

Programme identifier:

GB-GOV-10-R2HC_Phase_3

Start Date:

2018-08-31

Activity Status:

Implementation

Total Budget:

£4,000,000


Joint Global Health Trials Initiative

UK - Department of Health (DH)

The UK Department of Health and Social Care (DHSC) funds outstanding global health research through the National Institute for Health Research (NIHR). This programme is administered by the UK Medical Research Council (MRC), which reports activities under the UK Department for Business, Energy and Industrial Strategy (BEIS). NIHR disburses funds to MRC, which makes onwards disbursements to awardees. The aim of this programme is to generate new knowledge to contribute to improving health in low and middle income countries (LMICs). Priority will be given to proposals most likely to yield implementable results and designed to address the major causes of mortality or morbidity in LMICs.

Programme identifier:

GB-GOV-10-JGHT

Start Date:

2016-12-07

Activity Status:

Implementation

Total Budget:

£33,608,204.87


Coalition for Epidemic Preparedness Innovations (CEPI) - Development of vaccines against diseases with epidemic potential

UK - Department of Health (DH)

The Coalition for Epidemic Preparedness Innovations (CEPI) was formally launched at the World Economic Forum in Davos in January 2017. It is the only international alliance with a primary focus on developing vaccines for diseases with epidemic potential. CEPI’s initial focus has been on developing vaccines against Lassa Fever, Nipah virus and Middle Eastern Respiratory Syndrome (MERS) virus.

Programme identifier:

GB-GOV-10-PDP_CEPI

Start Date:

2018-12-14

Activity Status:

Implementation

Total Budget:

£30,000,000


Support to NIHR Coordinating Centres for global health research resourcing

UK - Department of Health (DH)

Support provided for resourcing at NIHR Coordinating Centres to enable them to carry out global health research activities.

Programme identifier:

GB-GOV-10-NIHR_CC

Start Date:

2017-11-09

Activity Status:

Implementation

Total Budget:

£16,362,954


NIHR Global Health Research Units and Groups: research call 1

UK - Department of Health (DH)

The NIHR's first Global Health Research call for Units and Groups. UK universities and research institutes were invited to submit applications, working in equitable partnerships with researchers in low- and middle-income countries (LMICs), to either expand (Units) or develop (Groups) their ambitions to deliver world-class applied global health research to address under-funded or under-researched global health areas specific to those countries.

Programme identifier:

GB-GOV-10-NIHR_GHRUG1

Start Date:

2017-04-01

Activity Status:

Implementation

Total Budget:

£133,059,868.32


NIHR Global Health Research Groups: research call 2

UK - Department of Health (DH)

The NIHR's second Global Health Research call for Groups. UK universities and research institutes were invited to submit applications, working in equitable partnerships with researchers in low- and middle-income countries (LMIC), to develop their ambitions to deliver world-class applied global health research to address under-funded or under-researched global health areas specific to those countries.

Programme identifier:

GB-GOV-10-NIHR_GHRG2

Start Date:

2018-04-01

Activity Status:

Implementation

Total Budget:

£49,251,378.99


Global Alliance for Chronic Diseases

UK - Department of Health (DH)

The UK Department of Health and Social Care (DHSC) funds outstanding global health research through the National Institute for Health Research (NIHR). The Global Alliance for Chronic Diseases (GACD) coordinates and supports research activities that address the prevention and treatment of chronic non-communicable diseases, on a global scale. The GACD is the first collaboration of major research funding agencies to specifically address chronic non-communicable diseases.

Programme identifier:

GB-GOV-10-GACD

Start Date:

2018-06-12

Activity Status:

Implementation

Total Budget:

£3,972,573.08


Grand Challenges Canada Global Mental Health Programme

UK - Department of Health (DH)

The UK Department of Health and Social Care (DHSC) funds outstanding global health research through the National Institute for Health Research (NIHR). This Programme is administered by Grand Challenges Canada (GCC). The National Institute for Health Research (NIHR) is contributing in partnership to GCC's Global Mental Health Programme.

Programme identifier:

GB-GOV-10-GCC

Start Date:

2019-10-01

Activity Status:

Implementation

Total Budget:

£6,000,000


Global Patient Safety Collaborative

UK - Department of Health (DH)

The main objective of the Global Patient Safety Collaborative (GPSC) is to secure and scale up global action on patient safety as well as to work in close collaboration with selected low- and middle-income countries (LMICs) in their quest to reduce the risk of avoidable harm and improve the safety of their national health care systems.

Programme identifier:

GB-GOV-10-GPSC

Start Date:

2018-09-03

Activity Status:

Implementation

Total Budget:

£1,500,075


Global Road Safety Facility (GRSF)

UK - Department of Health (DH)

The UK Department of Health and Social Care (DHSC) funds outstanding global health research through the National Institute for Health Research (NIHR). The World Bank’s Global Road Safety Facility aims to address the growing public health crisis of road traffic deaths and injuries in low- and middle-income countries (LMICs) through supporting the scale-up of scientific, technological and managerial capacities to effectively manage road safety.

Programme identifier:

GB-GOV-10-GRSF

Start Date:

2018-10-05

Activity Status:

Implementation

Total Budget:

£5,300,000


NIHR Research and Innovation for Global Health Transformation: Call 1

UK - Department of Health (DH)

The National Institute for Health Research (NIHR)’s first Research and Innovation for Global Health Transformation (RIGHT) call. RIGHT funds cutting-edge interdisciplinary applied health research in key areas in in low- and middle-income countries (LMICs) where a strategic and targeted investment can result in a transformative impact. RIGHT Call 1 addresses research in three key areas: epilepsy, infection-related cancers and severe stigmatising skin diseases. UK universities and research institutes were invited to submit applications including a co-applicant or joint lead applicant from an LMIC relevant to the research proposal. Research must be focused on improving the health and welfare of people in LMICs.

Programme identifier:

GB-GOV-10-RIGHT_1

Start Date:

2019-09-01

Activity Status:

Implementation

Total Budget:

£33,760,394


UK Public Health Rapid Support Team - Rapid investigation and response

UK - Department of Health (DH)

Created in 2016, the UK-PHRST is the primary arm of Her Majesty’s Government to provide and coordinate the UK’s public health response to outbreaks in LMICs. The UK-PHRST is a unique collaboration between Public Health England and the London School of Hygiene and Tropical Medicine with input from a number of academic partners. The UK-PHRST’s remit covers outbreak response, research, and capacity building, as components of its integrated triple mandate: • Rapidly investigate and respond to disease outbreaks at their source in LMICs eligible for UK Official Development Assistance (ODA), with the aim of stopping a public health threat from becoming a broader health emergency • Conduct research to generate an evidence base for best practice in epidemic preparedness and response • Build capacity for improved and rapid national response to disease outbreaks in LMICs and contribute to supporting implementation of IHR at the request of national governments or international stakeholders such as WHO. The UK-PHRST rapidly deploys a standing team of multidisciplinary public health professionals and researchers as required in countries that are a priority for the UK’s ODA programme. The UK-PHRST full-time Core Deployable Team consists of specialists in epidemiology, laboratory microbiology, infection prevention and control, clinical case management and clinical research, social science, data management and logistical support who are available to deploy within 48 of an approved request. Reservists and Field Epidemiology Training Programme (FETP) Fellows complement this team, providing surge capacity and specialist expertise when needed. The UK-PHRST is financed through UK Official Development Assistance (ODA) funding through the Department of Health and Social Care. The UK-PHRST Director is the accountable person to the UK Government, through PHE, for delivery of the UK-PHRST objectives.

Programme identifier:

GB-GOV-10-UKPHRST-PHE

Start Date:

2016-04-01

Activity Status:

Implementation

Total Budget:

£12,682,451


International Health Regulations (IHR) Strengthening project

UK - Department of Health (DH)

The project enables scientific and technical capability to be mobilised for increased international engagement, significantly scaling up UK capacity to respond to WHO and country demand for support on IHR. This will enhance global, and country level health security and strengthen UK preparedness and capacity to respond to future threats. The project works to build technical capability, strengthen leadership, and develop sustainable public health systems through provision of technical expertise to support and enhance WHO’s IHR strengthening efforts globally, particularly with Joint External Evaluation and National Action Planning activities. It does this through developing trusted institutional linkages, building long term partnerships and professional relationships at country and regional level. The project works at national level in partnerships with NPHIs and Health Ministries, providing targeted support to 4 countries (Ethiopia, Nigeria, Pakistan, and Zambia). At a regional level the project works with bodies such as Africa CDC and the Eastern Mediterranean Public Health Network (EMPHNET) as well as WHO regional offices. Through regional support, technical expertise will extend global health security capacity building to reach countries that may otherwise be neglected in terms of donor support. This will strengthen regional resilience networks for prevention, detection and response to future outbreaks.

Programme identifier:

GB-GOV-10-IHR-PHE

Start Date:

2016-11-21

Activity Status:

Implementation

Total Budget:

£23,679,613.78


Fleming Fund – Country and Regional Grants and Fellowships Programme

UK - Department of Health (DH)

The Fleming Fund helps low- and middle-income countries to fight antimicrobial resistance. A management agent has been appointed to deliver: country grants 24 low- and middle-income countries, regional grants in West Africa, East and Southern Africa, South Asia and South East Asia, and a global fellowships programme. These initiatives aim to improve laboratory capacity and diagnosis as well as data and surveillance of antimicrobial resistance (AMR).

Programme identifier:

GB-GOV-10-FF_MA

Start Date:

2016-10-10

Activity Status:

Implementation

Total Budget:

£258,497,532.75


Fleming Fund - ODI Fellowships

UK - Department of Health (DH)

The economic fellowship scheme supports international secondments of a cadre of skilled health economists to low- and middle-income one-health Ministries, such as Health, Agriculture and Environment. The programme is designed to uplift and build the capacity of Fleming Fund partner countries in several core economic competencies that underpin the development of evidence-based policy relevant to addressing antimicrobial resistance (AMR).

Programme identifier:

GB-GOV-10-FF_ODI_Fellowships

Start Date:

2018-12-01

Activity Status:

Implementation

Total Budget:

£1,505,065.60


UK Public Health Rapid Support Team - Research

UK - Department of Health (DH)

""Created in 2016, the UK-PHRST is the primary arm of Her Majesty’s Government to provide and coordinate the UK’s public health response to outbreaks in LMICs. The UK-PHRST is a unique collaboration between Public Health England and the London School of Hygiene and Tropical Medicine with input from a number of academic partners. The UK-PHRST’s remit covers outbreak response, research, and capacity building, as components of its integrated triple mandate: • Rapidly investigate and respond to disease outbreaks at their source in LMICs eligible for UK Official Development Assistance (ODA), with the aim of stopping a public health threat from becoming a broader health emergency • Conduct research to generate an evidence base for best practice in epidemic preparedness and response • Build capacity for improved and rapid national response to disease outbreaks in LMICs and contribute to supporting implementation of IHR at the request of national governments or international stakeholders such as WHO. The UK-PHRST rapidly deploys a standing team of multidisciplinary public health professionals and researchers as required in countries that are a priority for the UK’s ODA programme. The UK-PHRST full-time Core Deployable Team consists of specialists in epidemiology, laboratory microbiology, infection prevention and control, clinical case management and clinical research, social science, data management and logistical support who are available to deploy within 48 of an approved request. Reservists and Field Epidemiology Training Programme (FETP) Fellows complement this team, providing surge capacity and specialist expertise when needed. The UK-PHRST is financed through UK Official Development Assistance (ODA) funding through the Department of Health and Social Care. The UK-PHRST Director is the accountable person to the UK Government, through PHE, for delivery of the UK-PHRST objectives.""

Programme identifier:

GB-GOV-10-UKPHRST-LSHTM

Start Date:

2016-04-01

Activity Status:

Implementation

Total Budget:

£3,445,469.78


Global Antimicrobial Resistance Innovation Fund (GAMRIF) – UK-Argentina: tools to tackle AMR in the Environment

UK - Department of Health (DH)

This is a bilateral partnership with Argentina to support research to tackle antimicrobial resistance (AMR) in agriculture and the impact on the environment. Successful projects are a partnership of UK companies and research orgnisations, with Argentinian companies and research organisations. The competition and partnership will be delivered in the UK by the Biotechnology and Biological Sciences Research Council (BBSRC) in partnership with the Natural Environment Research Council (NERC), both part of UK Research and Innovation (UKRI), and delivered and matched-funded, on a resource basis, by the National Scientific and Technical Research Council (CONICET) in Argentina.

Programme identifier:

GB-GOV-10-GAMRIF-WP4-UK-Argentina

Start Date:

2018-04-01

Activity Status:

Implementation

Total Budget:

£4,999,999


World Health Organization (WHO) UK annual assessed contribution

UK - Department of Health (DH)

The UK Department of Health and Social Care (DHSC) annual assessed contribution to the World Health Organization (WHO).

Programme identifier:

GB-GOV-10-WHO_UK_contribution

Start Date:

2015-01-01

Activity Status:

Implementation

Total Budget:

£72,960,000




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